ArticlePloS one2017
The U-box family genes in Medicago truncatula: Key elements in response to salt, cold, and drought stresses.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Genome-wide identification and expression analysis of chickpea U-box E3 ligases identifies CaPUB4 and CaPUB16 as candidate responsive genes for abiotic stress tolerance.Journal of applied genetics · 2026Article
- Combining two high-density QTL maps with a reference genome to identify candidate genes for morphology, yield, and biotic resistance in faba bean (Frontiers in plant science · 2026Article
- Combination of QTL mapping and GWAS for fine mapping and gene mining of drought tolerance and seed yield components in faba bean (Vicia faba L.).BMC plant biology · 2025Article
- Genome-Wide Identification and Expression Analysis of Mitochondrial Dicarboxylate Carriers (DICs) in Medicago Under Aluminum Stress.Plants (Basel, Switzerland) · 2025Article
- Genomic signatures of local adaptation to precipitation and solar radiation in kiwifruit.Plant diversity · 2025Article
- Genome-Wide Identification ofPlants (Basel, Switzerland) · 2025Article
- Genome-wide analysis of the KCS gene family in Medicago truncatula and their expression profile under various abiotic stress.Scientific reports · 2025Article
- Genome-Wide Identification and Expression Analysis of thePlants (Basel, Switzerland) · 2024Article
- Genome-wide identification and transcriptome profiling expression analysis of the U-box E3 ubiquitin ligase gene family related to abiotic stress in maize (Zea mays L.).BMC genomics · 2024Article
- Genome-wide identification ofFrontiers in genetics · 2024Article
- The genomic and epigenetic footprint of local adaptation to variable climates in kiwifruit.Horticulture research · 2023Article
- Genome-Wide Identification of the U-Box E3 Ubiquitin Ligase Gene Family in Cabbage (Plants (Basel, Switzerland) · 2023Article
- Physiological and transcriptomic responses to cold waves of the most cold-tolerant mangrove,Frontiers in plant science · 2023Article
- The activity of the stress modulated Arabidopsis ubiquitin ligases PUB46 and PUB48 is partially redundant.Plant signaling & behavior · 2022Article
- Classification and Expression Profile of the U-Box E3 Ubiquitin Ligase Enzyme Gene Family in Maize (Plants (Basel, Switzerland) · 2022Article
- Article
- Identification, characterization, and expression profiling of the putativeFrontiers in microbiology · 2022Article
- Genome-Wide Analysis of U-box E3 Ubiquitin Ligase Family in Response to ABA Treatment inFrontiers in plant science · 2022Article
- Identification and expression analysis ofPlant signaling & behavior · 2021Article
- Identification of RNA helicases inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ubiquitination pathway regulates growth, development, and stress responses in plants, and the U-box protein family of ubiquitin ligases has important roles in this pathway. Here, 64 putative U-box proteins were identified in the Medicago truncatula genome. In addition to the conserved U-box motif, other functional domains, such as the ARM, kinase, KAP, and WD40 domains, were also detected. Phylogenetic analysis of the M. truncatula U-box proteins grouped them into six subfamilies, and chromosomal mapping and synteny analyses indicated that tandem and segmental duplications may have contributed to the expansion and evolution of the U-box gene family in this species. Using RNA-seq data from M. truncatula seedlings subjected to three different abiotic stresses, we identified 33 stress-inducible plant U-box genes (MtPUBs). Specifically, 25 salinity-, 15 drought-, and 16 cold-regulated MtPUBs were detected. Among them, MtPUB10, MtPUB17, MtPUB18, MtPUB35, MtPUB42, and MtPUB44 responded to all three stress conditions. Expression profiling by qRT-PCR was consistent with the RNA-seq data, and stress-related elements were identified in the promoter regions. The present findings strongly indicate that U-box proteins play critical roles in abiotic stress response in M. truncatula.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.