Evidence map›Paper›PMID 28771501›Full record

ArticlePloS one2017

Obliteration of bacterial growth and biofilm through ROS generation by facilely synthesized green silver nanoparticles.

Shariq Qayyum, Mohammad Oves, Asad U Khan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 162 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Biosynthesis and Characterization ofNanomaterials (Basel, Switzerland) · 2026
    Article
  6. Antimicrobial Resistance: The Answers.British journal of biomedical science · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Gallic acid synergistically enhances the antibacterial activity of azithromycin in MRSA.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Evaluation of the Effect ofPathogens (Basel, Switzerland) · 2023
    Article
  17. Use ofMolecules (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shariq QayyumMedical Microbiology and Molecular Biology Laboratory Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India.
Mohammad OvesCenter of Excellence in Environmental Studies (CEES), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Asad U KhanMedical Microbiology and Molecular Biology Laboratory Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India.
Aligarh Muslim University · INKing Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mangifera indica inflorescence aqueous extract was utilized for production of green AgNPs. Synthesized AgNPs were characterized by UV-vis spectrophotometry, XRD, TEM, FESEM and particles size analyzer. AgNPs showed minimum inhibitory concentrations (MICs) of 8 μg ml-1 and 16 μg ml-1 for Gram negative (K. pneumoniae, P. aeruginosa and E. coli) and Gram positive (S. mutans and S. aureus) strains, respectively which was relatively quite low compared to chemically synthesized silver nanoparticles. AgNPs inhibited 80% and 75% biofilms of E. coli and S. mutans respectively as observed quantitatively by crystal violet assay. Qualitative biofilm inhibition was observed using SEM and CLSM. AgNPs adsorbed catheter also resisted the growth of biofilm on its surface displaying its possible future applications. AgNPs interaction with bacteria lead to bacterial membrane damage as observed by SEM and TEM. The membrane damage was confirmed by detecting leakage of proteins and reducing sugars from treated bacterial cells. AgNPs generated ROS on interaction with bacterial cells and this ROS production can be one of the possible reasons for their action. AgNPs exhibited no toxic effect on the cell viability of HeLa cell line.

Indexed as

Metal NanoparticlesBacteriaBiofilmsDNA CleavageGreen Chemistry TechnologyHeLa CellsHumansNanotechnologyParticle SizeReactive Oxygen SpeciesSilverReactive Oxygen SpeciesSilver

Identifiers

PMID28771501
PMCPMC5542591
OpenAlexW2744331467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.