Evidence map›Paper›PMID 28771478›Full record

ArticlePloS one2017

Patients in palliative care-Development of a predictive model for anxiety using routine data.

Sonja Hofmann, Stephanie Hess, Carsten Klein, Gabriele Lindena, Lukas Radbruch, Christoph Ostgathe

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Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sonja HofmannDepartment of Palliative Medicine, Universitätsklinikum Erlangen, CCC Erlangen-EMN, Friedrich- Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Stephanie HessDepartment of Anaesthesiology, Universitätsklinikum Erlangen, CCC Erlangen-EMN, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Carsten KleinDepartment of Palliative Medicine, Universitätsklinikum Erlangen, CCC Erlangen-EMN, Friedrich- Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Gabriele LindenaClinical Analysis, Research and Application (CLARA), Kleinmachnow, Germany.
Lukas RadbruchDepartment of Palliative Medicine, University Hospital of Bonn, Bonn, Germany.
Christoph OstgatheDepartment of Palliative Medicine, Universitätsklinikum Erlangen, CCC Erlangen-EMN, Friedrich- Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnxiety is one of the most common psychological symptoms in patients in a palliative care situation. This study aims to develop a predictive model for anxiety using data from the standard documentation routine.

methodsData sets of palliative care patients collected by the German quality management benchmarking system called Hospice and Palliative Care Evaluation (HOPE) from 2007 to 2011 were randomly divided into a training set containing two-thirds of the data and a test set with the remaining one-third. We dichotomized anxiety levels, proxy rated by medical staff using the validated HOPE Symptom and Problem Checklist, into two groups with no or mild anxiety versus moderate or severe anxiety. Using the training set, a multivariable logistic regression model was developed by backward stepwise selection. Predictive accuracy was evaluated by the area under the receiver operating characteristic curve (AUC) based on the test set.

resultsAn analysis of 9924 data sets suggests a predictive model for anxiety in patients receiving palliative care which contains gender, age, ECOG, living situation, pain, nausea, dyspnea, loss of appetite, tiredness, need for assistance with activities of daily living, problems with organization of care, medication with sedatives/anxiolytics, antidepressants, antihypertensive drugs, laxatives, and antibiotics. It results in a fair predictive value (AUC = 0.72).

conclusionsRoutinely collected data providing individual-, disease- and therapy-related information contain valuable information that is useful for the prediction of anxiety risks in patients receiving palliative care. These findings could thus be advantageous for providing appropriate support for patients in palliative care settings and should receive special attention in future research.

Indexed as

Models, StatisticalActivities of Daily LivingAgedAnxietyFemaleHumansMaleMiddle AgedPalliative CareROC Curve

Identifiers

PMID28771478
PMCPMC5542653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.