Evidence map›Paper›PMID 28771213›Full record

ReviewMolecules (Basel, Switzerland)2017

Essential Oils and Their Constituents: An Alternative Source for Novel Antidepressants.

Damião P de Sousa, Rayanne H N Silva, Epifanio F da Silva, Elaine C Gavioli

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Application ofMolecules (Basel, Switzerland) · 2024
    Article
  5. Investigation of the Molecular Mechanisms Underlying the Therapeutic Effect ofCombinatorial chemistry & high throughput screening · 2024
    Article
  6. Antidepressant and anxiolytic potential ofFrontiers in pharmacology · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Inhalation AromatherapyFrontiers in pharmacology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. (-)-BioMed research international · 2020
    Article
  17. Article
  18. The harmful effects of acute PMScientific reports · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Damião P de SousaDepartamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa, PB 58051-970, Brazil. damiao_desousa@yahoo.com.br.
Rayanne H N SilvaDepartamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, João Pessoa, PB 58051-970, Brazil. rayanne_nasci@hotmail.com.
Epifanio F da SilvaDepartamento de Biofísica e Farmacologia, Universidade Federal do Rio Grande do Norte, Natal, RN 59078-970, Brazil. epifaniofsilva@hotmail.com.
Elaine C GavioliDepartamento de Biofísica e Farmacologia, Universidade Federal do Rio Grande do Norte, Natal, RN 59078-970, Brazil. egavioli@hotmail.com.
Universidade Federal da Paraíba · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a disease that has affected a high proportion of the world's population and people of different ages, incapacitating them from good performance at work and in social relationships, and causing emotional disorders to millions of families. Therefore, the search for new therapeutic agents is considered a priority for the discovery of more effective forms of treatment. In this review, studies of essential oils and their constituents in experimental models related to depression are discussed. The mechanisms of action of the oils and the presence of psychoactive constituents in their chemical compositions are discussed. The data in the review show the therapeutic potential of essential oils and their chemical constituents for use in depressive disorders. Advanced studies using humans are needed to confirm the antidepressant properties described in animals.

Indexed as

Antidepressive AgentsModels, BiologicalOils, VolatileAnimalsDepressionHumansAntidepressive AgentsOils, Volatileanimal modelsantidepressantmajor depressionnatural productsoilterpene

Identifiers

PMID28771213
PMCPMC6152054
OpenAlexW2743008654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.