Evidence map›Paper›PMID 28771179›Full record

Trial reportInternational journal of molecular sciences2017

Leptin Receptor Gene Variant rs11804091 Is Associated with BMI and Insulin Resistance in Spanish Female Obese Children: A Case-Control Study.

Josune Olza, Azahara I Rupérez, Mercedes Gil-Campos, Rosaura Leis, Ramón Cañete, Rafael Tojo, Ángel Gil, Concepción M Aguilera

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Leptin Receptor Compound Heterozygosity in Humans and Animal Models.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Josune OlzaDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Institute of Nutrition and Food Technology, University of Granada, Av. Del Conocimiento s/n., 18016 Granada, Spain. jolza@ugr.es.
Azahara I RupérezDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Institute of Nutrition and Food Technology, University of Granada, Av. Del Conocimiento s/n., 18016 Granada, Spain. azahararuperez@ugr.es.
Mercedes Gil-CamposCIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. mercedes_gil_campos@yahoo.es.
Rosaura LeisCIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. mariarosaura.leis@usc.es.
Ramón CañeteCIBER Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. em1caesr@uco.es.
Rafael TojoUnit of Investigation in Nutrition, Growth and Human Development of Galicia, Paediatric Department, Clinic University Hospital of Santiago, University of Santiago de Compostela, Travesia de Choupana, 15706 Galicia, Spain rafael.tojo@usc.es. rafael.tojo@usc.es.
Ángel GilDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Institute of Nutrition and Food Technology, University of Granada, Av. Del Conocimiento s/n., 18016 Granada, Spain. agil@ugr.es.
Concepción M AguileraDepartment of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Institute of Nutrition and Food Technology, University of Granada, Av. Del Conocimiento s/n., 18016 Granada, Spain. caguiler@ugr.es.
Universidad de Granada · ESInstituto de Salud Carlos III · ESRafael Advanced Defense Systems (Israel) · ILUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptin is an endocrine hormone that has a critical role in body weight homoeostasis and mediates its effects via the leptin receptor (LEPR). Common polymorphisms in the genes coding leptin receptors have been associated with metabolic abnormalities. We assessed the association of 28

Indexed as

Body Mass IndexModels, BiologicalObesityPolymorphism, Single NucleotideReceptors, LeptinAdolescentCase-Control StudiesChildFemaleHumansInsulin ResistanceMaleSex FactorsSpainReceptors, Leptinchildgenetic polymorphisminsulin resistanceLEPR geneobesity

Identifiers

PMID28771179
PMCPMC5578080
OpenAlexW2740648938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.