Evidence map›Paper›PMID 28771073›Full record

ArticleVirulence2018

Co-occurrence of 3 different resistance plasmids in a multi-drug resistant Cronobacter sakazakii isolate causing neonatal infections.

Lining Shi, Quanhui Liang, Zhe Zhan, Jiao Feng, Yachao Zhao, Yong Chen, Mei Huang, Yigang Tong, Weili Wu, Weijun Chen and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Virulence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

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  6. Identification, Typing and Drug Resistance ofFoods (Basel, Switzerland) · 2023
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  7. First report of coexistence ofFrontiers in microbiology · 2023
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  9. Characterization ofMicroorganisms · 2022
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  10. Article
  11. Genomic Characterization ofFrontiers in microbiology · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Co-Occurrence ofInfection and drug resistance · 2020
    Article
  16. Analysis of the Molecular Diversity AmongFrontiers in microbiology · 2020
    Article
  17. Article
  18. Article
  19. In Vitro Susceptibility and Florfenicol Resistance inInternational journal of genomics · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Lining Shia Institute of Medical Laboratory Sciences, Jinling Hospital, School of Medicine, Nanjing University , Nanjing , China.
Quanhui Liangb Department of Clinical Laboratory , The First People's Hospital of Foshan , Foshan , China.
Zhe Zhanc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Jiao Fengc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Yachao Zhaoc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Yong Chena Institute of Medical Laboratory Sciences, Jinling Hospital, School of Medicine, Nanjing University , Nanjing , China.
Mei Huanga Institute of Medical Laboratory Sciences, Jinling Hospital, School of Medicine, Nanjing University , Nanjing , China.
Yigang Tongc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Weili Wud Beijing Institute of Genomics, Chinese Academy of Sciences , Beijing , China.
Weijun Chend Beijing Institute of Genomics, Chinese Academy of Sciences , Beijing , China.
Xiaojun Lia Institute of Medical Laboratory Sciences, Jinling Hospital, School of Medicine, Nanjing University , Nanjing , China.
Zhe Yinc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Jinglin Wangb Department of Clinical Laboratory , The First People's Hospital of Foshan , Foshan , China.
Dongsheng Zhouc State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing , China.
Institute of Microbiology · CNNanjing University · CNFirst People's Hospital of Foshan · CNBeijing Institute of Genomics · CNChinese Academy of Sciences · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cronobacter sakazakii 505108 was isolated from a sputum specimen of a neonate with severe pneumonia. C. sakazakii 505108 co-harbors 3 resistance plasmids of the IncHI2, IncX3, and IncFIB incomparability groups, respectively. These 3 plasmids have acquired several accessory modules, which carry an extremely large number of resistance genes, especially including those involved in resistance to carbapenems, aminoglycoside, tetracyclines, and phenicols and sulphonamide/trimethoprim. These plasmid-borne antibiotic resistance genes were associated with insertion sequences, integrons, and transposons, indicating that the assembly and mobilization of the corresponding accessory modules with complex chimera structures are facilitated by transposition and/or homologous recombination. This is the first report of fully sequence plasmids in clinical Cronobacter, which provides a deeper insight into plasmid-mediated multi-drug resistance in Cronobacter from hospital settings.

Indexed as

Genes, BacterialAnti-Bacterial AgentsBacterial ProteinsCronobacter sakazakiiDNA Transposable ElementsDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsEscherichia coliFemaleHumansInfant, NewbornMicrobial Sensitivity TestsPlasmidsPneumoniaTransformation, GeneticAnti-Bacterial AgentsBacterial ProteinsDNA Transposable Elementscarbapenem resistanceCronobacter sakazakiimulti-drug resistanceplasmids

Identifiers

PMID28771073
PMCPMC5955447
OpenAlexW2744276994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.