Evidence map›Paper›PMID 28770593›Full record

ArticleJournal of the International AIDS Society2017

Differentiated models of care for postpartum women on antiretroviral therapy in Cape Town, South Africa: a cohort study.

Landon Myer, Victoria Iyun, Allison Zerbe, Tamsin K Phillips, Kirsty Brittain, Elton Mukonda, Joanna Allerton, Cathy D Kalombo, Andile Nofemela, Elaine J Abrams

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  8. Predictors of Viremia in Postpartum Women on Antiretroviral Therapy.Journal of acquired immune deficiency syndromes (1999) · 2020
    Trial
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  10. Review
  11. Article
  12. International journal of MCH and AIDS · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Landon MyerCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Victoria IyunCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Allison ZerbeICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tamsin K PhillipsCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Kirsty BrittainCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Elton MukondaCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Joanna AllertonCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Cathy D KalomboProvincial Government of the Western Cape, Cape Town, South Africa.
Andile NofemelaCentre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Elaine J AbramsICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
University of Cape Town · ZAColumbia University · USGovernment of South Africa · ZA

Funding

Strategies to optimize ART services for maternal&child health: the MCH-ART studyR01HD074558 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABRAMS, ELAINE JANINE, MYER, BENJAMIN LANDON · 2012 to 2014
$2.9M
National Institute of Child Health and Human Development (NICHD) R01HD074558NICHD NIH HHS R01 HD074558
6 · The paper itself

Abstract

backgroundThe numbers of women initiating lifelong antiretroviral therapy (ART) during pregnancy and postpartum is increasing rapidly, presenting a burden on health systems and an urgent need for scalable models of care for this population. In a pilot project, we referred postpartum women who initiated ART during pregnancy to a community-based model of differentiated ART services.

methodsEligible women (on ART for at least 3 months with viral load (VL)<1000 copies/mL) were offered a choice of two ART models of care: (i) referral to an existing system of community-based 'adherence clubs', operated by lay counsellors with medication collection every 2-4 months; or (ii) referral to local primary healthcare clinics (PHC) with services provided by clinicians and medication collection every 1-2 months (local standard of care for postpartum ART). For evaluation, women were followed through 6-months postpartum with VL testing separate from either ART service.

resultsThrough September 2015, DISCUSSION: Adherence clubs may be a valuable model for postpartum women initiating ART in pregnancy, with good short-term outcomes observed during this critical period. To support optimal implementation, further research is needed into patient preferences for models of care, with consideration of integration of maternal and child health services, while ART adherence and retention require ongoing consideration in this population.

Indexed as

Postpartum PeriodAdultAnti-HIV AgentsCohort StudiesFemaleHIV InfectionsHumansPilot ProjectsPregnancyPregnancy Complications, InfectiousPrimary Health CareSouth AfricaViral LoadYoung AdultAnti-HIV Agentsadherence clubantiretroviral therapyHIVmaternal and child healthpostnatal careSouth Africa

Identifiers

PMID28770593
PMCPMC5577773
OpenAlexW2735813708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.