Cell Microencapsulation in Polyethylene Glycol Hydrogel Microspheres Using Electrohydrodynamic Spraying.

Mozhdeh Imaninezhad, Era Jain, Silviya Petrova Zustiak

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Hydrogel Microparticles for Bone Regeneration.Gels (Basel, Switzerland) · 2023
Review
Silk fibroin microgels as a platform for cell microencapsulation.Journal of materials science. Materials in medicine · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mozhdeh ImaninezhadDepartment of Biomedical Engineering, Saint Louis University, St. Louis, MO, 63103, USA.

Era JainDepartment of Biomedical Engineering, Washington University in Saint Louis, St. Louis, MO, 63130, USA.

Silviya Petrova ZustiakDepartment of Biomedical Engineering, Saint Louis University, St. Louis, MO, 63103, USA. szustiak@slu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microencapsulation of cells is beneficial for various biomedical applications, such as tissue regeneration and cell delivery. While a variety of techniques can be used to produce microspheres, electrohydrodynamic spraying (EHS) has shown promising results for the fabrication of cell-laden hydrogel microspheres in a wide range of sizes and in a relatively high-throughput manner. Here we describe an EHS technique for the fabrication of cell-laden polyethylene glycol (PEG) microspheres. We utilize mild hydrogel gelation chemistry and a combination of EHS parameters to allow for cell microencapsulation with high efficiency and viability. We also give examples on the effect of different EHS parameters such as inner diameter of the needle, voltage and flow rate on microsphere size and encapsulated cell viability.

Indexed as

MicrospheresBiocompatible MaterialsCell EncapsulationCell SurvivalElectrochemistryHumansHydrogelsPolyethylene GlycolsBiocompatible MaterialsHydrogelsPolyethylene GlycolsCell microencapsulationElectrosprayingHydrogelsMicrospheresPolyethylene glycol (PEG)

Identifiers

PMID28770494

DOI10.1016/j.jasms.2003.10.018

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.