Evidence map›Paper›PMID 28770401›Full record

ArticleLasers in medical science2017

In vitro studies to evaluate the effect of varying culture conditions and IPL fluencies on tenocyte activities.

Jihad A M Alzyoud, Ilyas M Khan, Sarah G Rees

Abstract read
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In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jihad A M AlzyoudFaculty of Allied Health Sciences, Hashemite University, Zarqa, Jordan. jalzyoud@yahoo.co.uk.
Ilyas M KhanSwansea University Medical School, ILS2, Swansea, SA2 8SS, UK.
Sarah G ReesSwansea University Medical School, Grove Building, Swansea, SA2 8PP, UK.
Swansea University · GBHashemite University · JO

Funding

J. A. M. Alzyoud is grateful to the Hashemite University, Jordan for their financial PhD sponsorship and support Not applicable
6 · The paper itself

Abstract

Tendons are dense, fibrous connective tissues which carry out the essential physiological role of transmitting mechanical forces from skeletal muscle to bone. From a clinical perspective, tendinopathy is very common, both within the sporting arena and amongst the sedentary population. Studies have shown that light therapy may stimulate tendon healing, and more recently, intense pulsed light (IPL) has attracted attention as a potential treatment modality for tendinopathy; however, its mechanism of action and effect on the tendon cells (tenocytes) is poorly understood. The present study therefore investigates the influence of IPL on an in vitro bovine tendon model. Tenocytes were irradiated with IPL at different devise settings and under variable culture conditions (e.g. utilising cell culture media with or without the pH indicator dye phenol red), and changes in tenocyte viability and migration were subsequently investigated using Alamar blue and scratch assays, respectively. Our data demonstrated that IPL fluencies of up to 15.9 J/cm

Indexed as

Intense Pulsed Light TherapyAnimalsCattleCell CountCell MovementCells, CulturedCell SurvivalSerumTenocytesIntense pulsed light (IPL)PhotobiostimulationPhototherapyTendinopathyTenocyte cell culture

Identifiers

PMID28770401
OpenAlexW2740065739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.