Evidence map›Paper›PMID 28770308›Full record

Observational studyPediatric cardiology2017

Hemoglobin Level at Stage 1 Discharge has No Impact on Inter-stage Growth and Stability in Single Ventricle Infants.

Claudia Delgado-Corcoran, Deborah U Frank, Stephanie Bodily, Chong Zhang, Katherine H Wolpert, Kathryn Lucas, Theodore J Pysher, Angela P Presson, Susan L Bratton

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia Delgado-CorcoranDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, School of Medicine, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT, 84108, USA. Claudia.Delgado@hsc.utah.edu.ORCID http://orcid.org/0000-0001-6449-225X
Deborah U FrankDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, School of Medicine, University of Virginia, HSC Box 800386, Charlottesville, VA, 22908-0386, USA.
Stephanie BodilyPrimary Children's Hospital, Intermountain Health Care, 100 N. Mario Cappechi Dr, Salt Lake City, UT, 84113, USA.
Chong ZhangDepartment of Internal Medicine, Division of Epidemiology, School of Medicine, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT, 84108, USA.
Katherine H WolpertDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, School of Medicine, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT, 84108, USA.
Kathryn LucasPrimary Children's Hospital, Intermountain Health Care, 100 N. Mario Cappechi Dr, Salt Lake City, UT, 84113, USA.
Theodore J PysherDepartment of Pathology, Division of Pediatric Pathology, School of Medicine, University of Utah, 100 N Mario Cappecchi Drive, Salt Lake City, UT, 84113, USA.
Angela P PressonDepartment of Internal Medicine, Division of Epidemiology, School of Medicine, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT, 84108, USA.
Susan L BrattonDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, School of Medicine, University of Utah, 295 Chipeta Way, P.O. Box 581289, Salt Lake City, UT, 84108, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemoglobin levels (Hgb) of infants with a single ventricle (SV) are traditionally maintained high to maximize oxygen-carrying capacity during stage 1 palliation (S1P), stage 2 palliation (S2P), and between stages (IS). A single-center observational cohort study was performed to determine if red blood cell transfusion during the convalescent phase of the S1P (late S1P transfusion) to achieve higher Hgb is associated with benefits during the IS including improved growth and decreased acute medical events. 137 infants <1 year with SV with SIP undergoing care from January 2008 to June 2015 were retrospectively evaluated. 78 (57%) infants received a late S1P transfusion. Median Hgb at S1P discharge was 15.9 g/dL (IQR 14.7-17.1) and median Hgb S2P at admission was 15.3 g/dL (IQR 14-16.3). Median daily weight gain was 22 g/day during IS (IQR 17-26) and median daily length gain was 0.09 cm (IQR 0.06-0.11). Hgb at SIP discharge was not associated with IS growth or fewer IS acute events. However, late S1P transfusions were associated with illness severity at S1P and more complicated S1P care. Our data suggest that SV infants after S1P, who are steadily recovering, do not benefit from late transfusion to raise their hemoglobin level at discharge.

Indexed as

Child DevelopmentCohort StudiesErythrocyte TransfusionFontan ProcedureHeart Defects, CongenitalHeart VentriclesHemoglobinsHumansInfantInfant, NewbornPalliative CarePatient DischargeRetrospective StudiesWeight GainHemoglobinsHemoglobin levelsInter-stage acute eventInter-stage periodSingle ventricle physiologyStage 1 and 2 palliationWeight and length gain

Identifiers

PMID28770308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.