Evidence map›Paper›PMID 28770233›Full record

ArticleJournal of immunology research2017

Airway Epithelial Repair by a Prebiotic Mannan Derived from

Christie F Michael, Christopher M Waters, Kim S LeMessurier, Amali E Samarasinghe, Chi Y Song, Kafait U Malik, D Betty Lew

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Gut Mycobiome and Asthma.Journal of fungi (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. AAnimals : an open access journal from MDPI · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Christie F MichaelDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38103, USA.
Christopher M WatersDepartment of Physiology, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38163, USA.
Kim S LeMessurierDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38103, USA.
Amali E SamarasingheDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38103, USA.
Chi Y SongDepartment of Pharmacology, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38163, USA.
Kafait U MalikDepartment of Pharmacology, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38163, USA.
D Betty LewDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38103, USA.ORCID 0000-0002-0857-5875
University of Tennessee Health Science Center · US

Funding

Eicosanoid-Induced Vascular Growth During InjuryR01HL079109 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI MALIK, KAFAIT U · 2005 to 2015
$3.3M
Mechanotransduction in Acute Lung InjuryR01HL094366 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI WATERS, CHRISTOPHER M · 2009 to 2012
$2.1M
CXCR4 signaling in lung epithelial repairR01HL123540 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI WATERS, CHRISTOPHER M · 2014 to 2017
$1.5M
Mannan, A Potential Therapeutic for AsthmaR41HL090108 · NHLBI · CUMBERLAND PHARMACEUTICALS, INC. · PI LEW, DUKHEE BETTY · 2009 to 2009
$112k
NHLBI NIH HHS R01 HL079109NHLBI NIH HHS R01 HL094366NHLBI NIH HHS R01 HL123540NHLBI NIH HHS R41 HL090108
6 · The paper itself

Abstract

In asthmatic airways, repeated epithelial damage and repair occur. No current therapy directly targets this process. We aimed to determine the effects of mannan derived from

Indexed as

PrebioticsAsthmaBronchiCell MovementCells, CulturedEpithelial CellsHumansKruppel-Like Factor 4Kruppel-Like Transcription FactorsLectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorReceptors, Cell SurfaceRespiratory MucosaSaccharomyces cerevisiaeKruppel-Like Factor 4Kruppel-Like Transcription FactorsLectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorPrebioticsReceptors, Cell Surface

Identifiers

PMID28770233
PMCPMC5523272
OpenAlexW2733718588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.