Evidence map›Paper›PMID 28770207›Full record

ArticleFrontiers in nutrition2017

Aberrant Cerebral Blood Flow in Response to Hunger and Satiety in Women Remitted from Anorexia Nervosa.

Christina E Wierenga, Amanda Bischoff-Grethe, Grace Rasmusson, Ursula F Bailer, Laura A Berner, Thomas T Liu, Walter H Kaye

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Christina E WierengaDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
Amanda Bischoff-GretheDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
Grace RasmussonDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
Ursula F BailerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
Laura A BernerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
Thomas T LiuDepartment of Radiology, University of California San Diego, La Jolla, CA, United States.
Walter H KayeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.
University of California, San Diego · US

Funding

Neurobiology of Feeding &Other Behaviors in BulimiaR01MH042984 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAYE, WALTER H · 1988 to 2013
$6.3M
NIMH NIH HHS R01 MH042984
6 · The paper itself

Abstract

The etiology of pathological eating in anorexia nervosa (AN) remains poorly understood. Cerebral blood flow (CBF) is an indirect marker of neuronal function. In healthy adults, fasting increases CBF, reflecting increased delivery of oxygen and glucose to support brain metabolism. This study investigated whether women remitted from restricting-type AN (RAN) have altered CBF in response to hunger that may indicate homeostatic dysregulation contributing to their ability to restrict food. We compared resting CBF measured with pulsed arterial spin labeling in 21 RAN and 16 healthy comparison women (CW) when hungry (after a 16-h fast) and after a meal. Only remitted subjects were examined to avoid the confounding effects of malnutrition on brain function. Compared to CW, RAN demonstrated a reduced difference in the Hungry - Fed CBF contrast in the right ventral striatum, right subgenual anterior cingulate cortex (

Indexed as

anorexia nervosaarterial spin labelingcerebral blood flowenergy metabolismhomeostatic regulationhunger

Identifiers

PMID28770207
PMCPMC5515860
OpenAlexW2737533958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.