Evidence map›Paper›PMID 28770104›Full record

ArticleThe journal of pathology. Clinical research2017

Immunoscore in mismatch repair-proficient and -deficient colon cancer.

Erkki-Ville Wirta, Toni Seppälä, Marjukka Friman, Juha Väyrynen, Maarit Ahtiainen, Hannu Kautiainen, Teijo Kuopio, Ilmo Kellokumpu, Jukka-Pekka Mecklin, Jan Böhm

Open access · goldAbstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 72 citations in OpenAlex.

  1. Tumour-infiltrating CD8British journal of cancer · 2019
    Trial
  2. Article
  3. Article
  4. Review
  5. Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. The Role of Nonmetastatic Lymph Nodes in the Survival of Colorectal Cancer: A Systematic Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Erkki-Ville WirtaDepartment of SurgeryCentral Finland Central HospitalJyväskyläFinland.
Toni SeppäläDepartment of SurgeryHelsinki University Central HospitalHelsinkiFinland.
Marjukka FrimanDepartment of PathologyCentral Finland Central HospitalJyväskyläFinland.
Juha VäyrynenDepartment of PathologyUniversity of OuluOuluFinland.
Maarit AhtiainenDepartment of Education and ResearchCentral Finland Central Hospital, Jyväskylä and University of Eastern FinlandKuopioFinland.
Hannu KautiainenDepartment of General Practice, Unit of Primary Health Care, Helsinki University Central HospitalUniversity of HelsinkiHelsinkiFinland.
Teijo KuopioDepartment of PathologyCentral Finland Central HospitalJyväskyläFinland.
Ilmo KellokumpuDepartment of SurgeryCentral Finland Central HospitalJyväskyläFinland.
Jukka-Pekka MecklinDepartment of SurgeryCentral Finland Central HospitalJyväskyläFinland.
Jan BöhmDepartment of PathologyCentral Finland Central HospitalJyväskyläFinland.
Central Finland Health Care District · FIHelsinki University Hospital · FIKuopio University Hospital · FIUniversity of Eastern Finland · FIUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate immune response and its prognostic significance in colon carcinomas using the previously described Immunoscore (IS). A population-based series of 779 colorectal cancers, operated on between 2000 and 2010, were classified according to tumour, node, metastasis (TNM) status, mismatch repair (MMR), and

Indexed as

AJCC/UICC stageBRAFcolon cancerimmunoscoremismatch repair status

Identifiers

PMID28770104
PMCPMC5527320
OpenAlexW2608667084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.