Evidence map›Paper›PMID 28769871›Full record

ReviewFrontiers in neurology2017

The Role of MicroRNAs in Aβ Deposition and Tau Phosphorylation in Alzheimer's Disease.

Juanjuan Zhao, Dongxu Yue, Ya Zhou, Li Jia, Hairong Wang, Mengmeng Guo, Hualin Xu, Chao Chen, Jidong Zhang, Lin Xu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Juanjuan ZhaoDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Dongxu YueDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Ya ZhouDepartment of Medical Physics, Zunyi Medical College, Guizhou, China.
Li JiaDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Hairong WangDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Mengmeng GuoDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Hualin XuDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Chao ChenDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Jidong ZhangDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Lin XuDepartment of Immunology, Zunyi Medical College, Guizhou, China.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD), with main clinical features of progressive impairment in cognitive and behavioral functions, is the most common degenerative disease of the central nervous system. Recent evidence showed that microRNAs (miRNAs) played important roles in the pathological progression of AD. In this article, we reviewed the promising role of miRNAs in both Aβ deposition and Tau phosphorylation, two key pathological characters in the pathological progression of AD, which might be helpful for the understanding of pathogenesis and the development of new strategies of clinical diagnosis and treatment of AD.

Indexed as

Alzheimer’s diseaseamyloid-betaamyloid precursor proteinmicroRNAsTau protein

Identifiers

PMID28769871
PMCPMC5513952
OpenAlexW2737500933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.