ArticleFrontiers in psychiatry2017
A Pilot Study of Possible Easy-to-Use Electrophysiological Index for Early Detection of Antidepressive Treatment Non-Response.
Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A New Index of Coordinated Posterior and Anterior Evoked EEG to Detect Recall Under Sedation - A Pilot Study.Scientific reports · 2019Trial
- Using the OPTIMAL Theory to Optimize Aerodynamics in Respiratory Training for Healthy Adults and Individuals With Parkinson's Disease.International journal of language & communication disordersTrial
- A novel 1-channel EEG marker may associate with perioperative cognitive change.Frontiers in systems neuroscience · 2026Article
- Markers of too little effort or too much alertness during neuropsychological assessment: Demonstration with perioperative changes.Brain and behavior · 2024Article
- Probing a neural unreliability account of auditory sensory processing atypicalities in Rett Syndrome.Journal of neurodevelopmental disorders · 2024Article
- A multimodal approach for the ecological investigation of sustained attention: A pilot study.Frontiers in human neuroscience · 2022Article
- Compensatory movement strategies differentially affect attention allocation and gait parameters in persons with Parkinson's disease.Frontiers in human neuroscience · 2022Article
- Identifying Recall Under Sedation by a Novel EEG Based Index of Attention-A Pilot Study.Frontiers in medicine · 2022Article
- Classification of Depression Through Resting-State Electroencephalogram as a Novel Practice in Psychiatry: Review.Journal of medical Internet research · 2020Review
- The successful discrimination of depression from EEG could be attributed to proper feature extraction and not to a particular classification method.Cognitive neurodynamics · 2020Article
- The Effects of Anesthetics on the Cortex-Lessons From Event-Related Potentials.Frontiers in systems neuroscience · 2020Article
- Neuropsychiatric Disorders as Erratic Attention Regulation - Lessons from Electrophysiology.The Psychiatric quarterly · 2019Review
- Monitoring Migraine Cycle Dynamics with an Easy-to-Use Electrophysiological Marker-A Pilot Study.Sensors (Basel, Switzerland) · 2018Article
- Monitoring Attention in ADHD with an Easy-to-Use Electrophysiological Index.Frontiers in human neuroscience · 2018Article
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Authors and funding
7 authors.
Funding
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Abstract
introductionThe evaluation of response to pharmacological treatment in MDD requires 4-8 weeks. Therefore, the ability to predict response, and especially lack of response to treatment, as early as possible after treatment onset or change, is of prime significance. Many studies have demonstrated significant results regarding the ability to use EEG and ERP markers, including attention-associated markers such as P300, for early prediction of response to treatment. But these markers are derived from long EEG/ERP samples, often from multiple channels, which render them impractical for frequent sampling. METHODS AND
resultsWe developed a new electrophysiological attention-associated marker from a single channel (two electrodes), using 1-min samples with auditory oddball stimuli. This work presents an initial evaluation of the ability to use this marker's dynamics between repetitive measures for early (<2 weeks) differentiation between responders and non-responders to antidepressive treatment, in 26 patients with various levels of depression and heterogeneous treatment interventions. The slope of change in the marker between early consecutive samples was negative in the non-responders, but not in the responders. This differentiation was stronger for patients suffering from severe depression (
conclusionThis pilot study supports the feasibility of the EEG marker for early recognition of treatment-resistant depression. If verified in large-scale prospective studies, it can contribute to research and clinical work.
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