Evidence map›Paper›PMID 28769767›Full record

ArticleFrontiers in cellular neuroscience2017

Pannexins Are Potential New Players in the Regulation of Cerebral Homeostasis during Sleep-Wake Cycle.

Valery I Shestopalov, Yuri Panchin, Olga S Tarasova, Dina Gaynullina, Vladimir M Kovalzon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Pannexins in the vasculature.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  4. Astrocytes at the heart of sleep: from genes to network dynamics.Cellular and molecular life sciences : CMLS · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pannexin 1 Transgenic Mice: Human Diseases and Sleep-Wake Function Revision.International journal of molecular sciences · 2021
    Article
  10. Neurobiology of sleep (Review).Experimental and therapeutic medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Valery I ShestopalovInstitute for Information Transmission Problems, Russian Academy of SciencesMoscow, Russia.
Yuri PanchinInstitute for Information Transmission Problems, Russian Academy of SciencesMoscow, Russia.
Olga S TarasovaInstitute for Information Transmission Problems, Russian Academy of SciencesMoscow, Russia.
Dina GaynullinaDepartment of Human and Animal Physiology, Faculty of Biology, M.V. Lomonosov Moscow State UniversityMoscow, Russia.
Vladimir M KovalzonInstitute for Information Transmission Problems, Russian Academy of SciencesMoscow, Russia.
Vavilov Institute of General Genetics · RU

Funding

The Role of Pannexin 1 Pathway in Ocular Hypertension Injury of Retinal Ganglion CellsR01EY021517 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SHESTOPALOV, VALERY I · 2012 to 2020
$3.1M
NEI NIH HHS R01 EY021517
6 · The paper itself

Abstract

During brain homeostasis, both neurons and astroglia release ATP that is rapidly converted to adenosine in the extracellular space. Pannexin-1 (Panx1) hemichannels represent a major conduit of non-vesicular ATP release from brain cells. Previous studies have shown that Panx1

Indexed as

cytokinesendotheliumglymphatic systemneurovascular couplingnon-REM sleeppannexinsprostaglandin D2purinergic system

Identifiers

PMID28769767
PMCPMC5511838
OpenAlexW2746697378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.