Evidence map›Paper›PMID 28769575›Full record

ArticleOncoTargets and therapy2017

Distinct prognostic values of alcohol dehydrogenase mRNA expression in pancreatic adenocarcinoma.

Xiwen Liao, Rui Huang, Xiaoguang Liu, Chuangye Han, Long Yu, Shijun Wang, Na Sun, Bopei Li, Xin Ning, Tao Peng

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

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  12. Use of Genome-Scale Integrated Analysis to Identify Key Genes and Potential Molecular Mechanisms in Recurrence of Lower-Grade Brain Glioma.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  13. Article
  14. Article
  15. Distinct Prognostic Values of Alcohol Dehydrogenase Family Members for Non-Small Cell Lung Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  16. Article
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  19. Characteristic miRNA expression signature and random forest survival analysis identify potential cancer-driving miRNAs in a broad range of head and neck squamous cell carcinoma subtypes.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Xiwen LiaoDepartment of Hepatobiliary Surgery.
Rui HuangDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi.
Xiaoguang LiuDepartment of Hepatobiliary Surgery.
Chuangye HanDepartment of Hepatobiliary Surgery.
Long YuDepartment of Hepatobiliary Surgery.
Shijun WangDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan.
Na SunDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi.
Bopei LiDepartment of Gastrointestinal Surgery.
Xin NingDepartment of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Tao PengDepartment of Hepatobiliary Surgery.
Guangxi Medical University · CNSecond Military Medical University · CNEastern Hepatobiliary Surgery Hospital · CNFirst Affiliated Hospital of GuangXi Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol dehydrogenase (ADH) isoenzymes have been reported as a potential diagnostic marker for pancreatic cancer, but their prognostic value in pancreatic cancer remains unclear. The aim of this investigation was to identify the prognostic value of ADH genes in human patients with pancreatic adenocarcinoma (PAAD). MATERIALS AND

methodsAn RNA sequencing dataset and corresponding survival profiles of PAAD were obtained from The Cancer Genome Atlas. Survival analysis and gene set enrichment analysis were used to investigate the prediction value and potential mechanism of ADH genes in PAAD prognosis.

resultsSurvival analysis of ADH genes suggests that a high expression of

conclusionOur data suggest that

Indexed as

alcohol dehydrogenaseGSEApancreatic adenocarcinomaprognosticTCGA

Identifiers

PMID28769575
PMCPMC5533474
OpenAlexW2736419894

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.