Evidence map›Paper›PMID 28769572›Full record

ArticleOncoTargets and therapy2017

miR-203 as a novel biomarker for the diagnosis and prognosis of colorectal cancer: a systematic review and meta-analysis.

Huajun Ye, Haibin Hao, Jincheng Wang, Renpin Chen, Zhiming Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huajun YeDepartment of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang.
Haibin HaoDepartment of General Surgery, Medical College of Nanchang University, Nanchang.
Jincheng WangDepartment of Medical Imaging, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People's Republic of China.
Renpin ChenDepartment of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang.
Zhiming HuangDepartment of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to systematically evaluate the diagnostic and prognostic value of miR-203 in patients with colorectal cancer. To explore the diagnostic performance of miR-203, eligible studies were identified from biomedical databases. Based on these results, 11 studies were pooled and included in this meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratios of miR-203 were 0.83 (95% confidence interval, CI: 0.78-0.86), 0.80 (95% CI: 0.77-0.83), and 19.27 (95% CI: 7.23-51.36) for the diagnosis of colorectal cancer. The area under the curve for miR-203 for diagnosing colorectal cancer was 0.89. Patients with higher expression of tissue miR-203 had poor overall survival (pooled hazard ratio: 1.63; 95% CI: 1.03-2.57,

Indexed as

colorectal cancerCRCdiagnosismiR-203prognosis

Identifiers

PMID28769572
PMCPMC5533489

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.