ReviewInternal medicine (Tokyo, Japan)2017
Longitudinally Extensive Transverse Myelitis and Optic Neuropathy Associated with Syphilitic Meningomyelitis and Human Immunodeficiency Virus Infection: A Case Report and Review of the Literature.
Review in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Mycoplasma pneumoniae infection and concurrent aquaporin-4-positive neuromyelitis optica spectrum disorder: a case report and literature review.BMC pediatrics · 2025Review
- A case report of acute idiopathic longitudinal extensive transverse myelitis.Turkish journal of physical medicine and rehabilitation · 2025Article
- Longitudinally extensive transverse myelitis with mycobacterium tuberculosis infection.Acta neurologica Belgica · 2023Article
- Treatment Challenges in a Severe Case of Syphilitic Myelitis With a Longitudinally Extensive Spinal Cord Lesion.The Neurohospitalist · 2022Article
- Clinical features of syphilitic myelitis with longitudinally extensive myelopathy on spinal magnetic resonance imaging.World journal of clinical cases · 2019Article
- Article
- Neurosyphilis Manifesting as Longitudinally Extensive Transverse Myelitis.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of co-infection with Treponema pallidum and human immunodeficiency virus (HIV) is increasing in developing and developed countries. The neurological complications of both infections occasionally occur simultaneously during a clinical course. We herein report the case of an HIV carrier with syphilitic meningomyelitis and subclinical optic neuropathy. The patient presumably had latent syphilis and slowly developed longitudinally extensive transverse myelitis (LETM). A cerebrospinal fluid examination confirmed the diagnosis of active neurosyphilis based on an elevated T. pallidum hemagglutination assay index. A change in the patient's immune status, possibly due to HIV, might have converted the syphilis from latent to active, leading to LETM of the spinal cord.
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Registered trials
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