Evidence map›Paper›PMID 28768965›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Reactivation of Occult Hepatitis B Virus Infection 27 Months after the End of Chemotherapy Including Rituximab for Malignant Lymphoma.

Junichi Muraishi, Michihiko Shibata, Yuichi Honma, Masaaki Hiura, Shintaro Abe, Masaru Harada

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Hepatitis B Reactivation in the Treatment of Non-Hodgkin Lymphoma.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junichi MuraishiThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.
Michihiko ShibataThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.
Yuichi HonmaThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.
Masaaki HiuraThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.
Shintaro AbeThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.
Masaru HaradaThird Department of Internal Medicine, Japan School of Medicine, University of Occupational and Environmental Health, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 68-year-old man with occult hepatitis B virus (HBV) infection was diagnosed with malignant lymphoma and achieved complete remission after treatment with a chemotherapy regimen including rituximab for 5 months. Entecavir (ETV) was also used during and after chemotherapy and was ended at 14 months after chemotherapy. However, reactivation of HBV was observed in blood tests, which showed not only elevation of HBV-DNA but also HBsAg and HBeAg, at 27 months after the end of chemotherapy. After restarting ETV, the HBV-DNA levels immediately subsided. In addition, anti-HBs became and remained positive at 31 months after chemotherapy. ETV was re-discontinued at 36 months after chemotherapy.

Indexed as

AgedAntibodies, Monoclonal, Murine-DerivedAntiviral AgentsGuanineHepatitis BHepatitis B AntibodiesHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansLymphomaMaleRituximabVirus ActivationAntibodies, Monoclonal, Murine-DerivedAntiviral AgentsentecavirGuanineHepatitis B AntibodiesHepatitis B e AntigensHepatitis B Surface AntigensRituximabentecavirHBVreactivationrituximab

Identifiers

PMID28768965
PMCPMC5577071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.