Evidence map›Paper›PMID 28768894›Full record

ArticleProceedings. Biological sciences2017

Phenotypic plasticity in reproductive effort: malaria parasites respond to resource availability.

Philip L G Birget, Charlotte Repton, Aidan J O'Donnell, Petra Schneider, Sarah E Reece

Open access · hybridAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Plastic responses ofBiology letters · 2025
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  6. Article
  7. Evolution of class-structured populations in periodic environments.Evolution; international journal of organic evolution · 2022
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Philip L G BirgetInstitutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK philipbirget@gmail.com.ORCID http://orcid.org/0000-0001-8239-5293
Charlotte ReptonInstitutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK.
Aidan J O'DonnellInstitutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK.
Petra SchneiderInstitutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK.
Sarah E ReeceInstitutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK.
Google (United States) · US

Funding

Wellcome Trust 202769/Z/16/Z
6 · The paper itself

Abstract

The trade-off between survival and reproduction is fundamental in the life history of all sexually reproducing organisms. This includes malaria parasites, which rely on asexually replicating stages for within-host survival and on sexually reproducing stages (gametocytes) for between-host transmission. The proportion of asexual stages that form gametocytes (reproductive effort) varies during infections-i.e. is phenotypically plastic-in response to changes in a number of within-host factors, including anaemia. However, how the density and age structure of red blood cell (RBC) resources shape plasticity in reproductive effort and impacts upon parasite fitness is controversial. Here, we examine how and why the rodent malaria parasite

Indexed as

Host-Parasite InteractionsAdaptation, PhysiologicalAnemiaAnimalsErythrocytesGenotypeMalariaPhenotypePlasmodium chabaudiReproductiongametocytesgenetic variationlife-history strategyphenotypic plasticityresource allocation trade-offreticulocytes

Identifiers

PMID28768894
PMCPMC5563815
OpenAlexW2741819645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.