ArticleJournal of virology2017
Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.
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Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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0cells of the map it votes in
35citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 49 citations in OpenAlex.
- Review
- Article
- Optimum level of NEDD4 and its interaction with nsP3 are crucial to facilitate efficient Chikungunya virus (CHIKV) infection.The Journal of general virology · 2025Article
- E3 Ubiquitin Ligase Smurf1 Regulates the Inflammatory Response in Macrophages and Attenuates Hepatic Damage during Betacoronavirus Infection.Pathogens (Basel, Switzerland) · 2024Article
- Marburg virus exploits the Rab11-mediated endocytic pathway in viral-particle production.Microbiology spectrum · 2024Article
- Molecular insights into the Ebola virus life cycle.Nature microbiology · 2024Review
- Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.PLoS biology · 2024Article
- WWP1 E3 ligase at the crossroads of health and disease.Cell death & disease · 2023Review
- Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities.bioRxiv : the preprint server for biology · 2023Article
- Article
- Mutation of Phenylalanine 23 of Newcastle Disease Virus Matrix Protein Inhibits Virus Release by Disrupting the Interaction between the FPIV L-Domain and Charged Multivesicular Body Protein 4B.Microbiology spectrum · 2023Article
- Potential antiviral effects of pantethine against SARS-CoV-2.Scientific reports · 2023Article
- Chaperone-assisted selective autophagy targets filovirus VP40 as a client and restricts egress of virus particles.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles.Journal of virology · 2022Article
- Negative-sense RNA viruses: An underexplored platform for examining virus-host lipid interactions.Molecular biology of the cell · 2021Review
- Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.The EMBO journal · 2021Article
- Review
- Compound FC-10696 Inhibits Egress of Marburg Virus.Antimicrobial agents and chemotherapy · 2021Article
- P300-mediated NEDD4 acetylation drives ebolavirus VP40 egress by enhancing NEDD4 ligase activity.PLoS pathogens · 2021Article
- Angiomotin Counteracts the Negative Regulatory Effect of Host WWOX on Viral PPxY-Mediated Egress.Journal of virology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 3 countries.
Ziying HanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cari A SagumDepartment of Epigenetics and Molecular Carcinogenesis, M.D. Anderson Cancer Center, University of Texas, Smithville, Texas, USA.
Fumio TakizawaDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Gordon RuthelDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Corbett T BerryDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jing KongDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
J Oriol SunyerDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bruce D FreedmanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mark T BedfordDepartment of Epigenetics and Molecular Carcinogenesis, M.D. Anderson Cancer Center, University of Texas, Smithville, Texas, USA.
Sachdev S SidhuDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Marius SudolDepartment of Physiology, Institute for Molecular and Cell Biology (A*STAR), National University of Singapore, Singapore.
Ronald N HartyDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA rharty@vet.upenn.edu.
University of Pennsylvania · USThe University of Texas MD Anderson Cancer Center · USNational University of Singapore · SGUniversity of Toronto · CA
Funding
Host-Oriented Therapeutics Targeting Filovirus Budding.R33AI102104 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2014 to 2016
$1.4MFLIM system, resonant scanner, and UV laser for 2 photon microscopeS10RR027128 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FREEDMAN, BRUCE D · 2010 to 2010
$496kInnate Immune Regulation of Intracellular Pathways Involved in Filovirus BuddingR21AI103785 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2014 to 2015
$440kHost-Oriented Therapeutics Targeting Filovirus Budding.R21AI102104 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HARTY, RONALD N · 2012 to 2013
$423kDEVELOPMENT OF SMALL MOLECULE THERAPEUTICS AGAINST RNA VIRUSESR41AI113952 · NIAID · FOX CHASE CHEMICAL DIVERSITY CENTER, INC · PI HARTY, RONALD N · 2015 to 2015
$300kNCRR NIH HHS S10 RR027128NIAID NIH HHS R21 AI102104NIAID NIH HHS R21 AI103785NIAID NIH HHS R33 AI102104NIAID NIH HHS R41 AI113952
Abstract
Ebola virus (EBOV) is a member of the
Indexed as
Host-Pathogen InteractionsVirus ReleaseEbolavirusHEK293 CellsHumansNucleoproteinsRNA, Small InterferingUbiquitinationUbiquitin-Protein LigasesViral Core ProteinsViral Matrix ProteinsVirionVirus AssemblyNucleoproteinsnucleoprotein VP40, Ebola virusRNA, Small InterferingUbiquitin-Protein LigasesViral Core ProteinsViral Matrix ProteinsWWP1 protein, humanbuddingE3 ubiquitin ligaseEbola virusL-domainPPXYVLPsVP40WW domainWWP1
Identifiers
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Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.