Evidence map›Paper›PMID 28768806›Full record

Trial reportScience translational medicine2017

A phenotypically and functionally distinct human T

Erik Wambre, Veronique Bajzik, Jonathan H DeLong, Kimberly O'Brien, Quynh-Anh Nguyen, Cate Speake, Vivian H Gersuk, Hannah A DeBerg, Elizabeth Whalen, Chester Ni and 6 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Science translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed.

  1. Trial
  2. HLA-DRAllergy · 2025
    Trial
  3. Trial
  4. Trial
  5. Trial
  6. CD8Nature communications · 2022
    Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Expansion of the CD4The Journal of allergy and clinical immunology · 2020
    Trial
  15. Trial
  16. Article
  17. T Cell Thoughts.Immunological reviews · 2026
    Review
  18. Review
  19. Review
  20. Article

150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Erik WambreBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA. ewambre@benaroyaresearch.org.ORCID http://orcid.org/0000-0002-3628-0011
Veronique BajzikBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0003-4518-8011
Jonathan H DeLongBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-2032-8228
Kimberly O'BrienBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-6646-7514
Quynh-Anh NguyenBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0001-8288-0678
Cate SpeakeBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0003-1480-4272
Vivian H GersukBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0003-4123-9926
Hannah A DeBergBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-5263-158X
Elizabeth WhalenBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0001-8862-2573
Chester NiBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-5350-1090
Mary FarringtonVirginia Mason Medical Center, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-2589-830X
David JeongVirginia Mason Medical Center, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-9322-6820
David RobinsonVirginia Mason Medical Center, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-9956-8100
Peter S LinsleyBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0002-8960-4307
Brian P VickeryAimmune Therapeutics, Brisbane, CA 94005, USA.
William W KwokBenaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA.ORCID http://orcid.org/0000-0003-4843-4599

Funding

Induction and signature of pathogenic T cells in allergyR01AI108839 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI WAMBRE, ERIK · 2014 to 2018
$2.1M
Single Cell Transcriptome Analysis of Islet Antigen Reactive Memory CD4+ T Cells in Establshed T1DDP3DK110867 · NIDDK · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI LINSLEY, PETER S · 2016 to 2016
$510k
NIAID NIH HHS R01 AI108839NIDDK NIH HHS DP3 DK110867
6 · The paper itself

Abstract

Allergen-specific type 2 helper T (T

Indexed as

AdolescentAdultAllergensArachisChildChild, PreschoolGene Expression ProfilingGene Expression RegulationHumansHypersensitivityImmunotherapyPhenotypeTh2 CellsT-Lymphocyte SubsetsYoung AdultAllergens

Identifiers

PMID28768806
PMCPMC5987220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.