Evidence map›Paper›PMID 28768770›Full record

ArticleThe Journal of biological chemistry2017

NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic β-cells.

Yi Wu, Dale A Fortin, Veronica A Cochrane, Pei-Chun Chen, Show-Ling Shyng

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. CCK-sensitive C fibers activate NTS leptin receptor-expressing neurons via NMDA receptors.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Subcellular trafficking and endocytic recycling of KAmerican journal of physiology. Cell physiology · 2022
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Ion Channels of the Islets in Type 2 Diabetes.Journal of molecular biology · 2020
    Review
  17. Adipokine Leptin Co-operates With Mechanosensitive CaFrontiers in cell and developmental biology · 2020
    Article
  18. Review
  19. Review
  20. Leptin-induced Trafficking of KInternational journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yi WuFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239 and.
Dale A FortinFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239 and.
Veronica A CochraneFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239 and.
Pei-Chun Chenthe Department of Physiology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan pcchen@mail.ncku.edu.tw.
Show-Ling ShyngFrom the Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon 97239 and shyngs@ohsu.edu.ORCID 0000-0002-8230-8820
Oregon Health & Science University · USNational Cheng Kung University · TW

Funding

KATP channels and insulin secretionR01DK057699 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHYNG, SHOW-LING · 2001 to 2019
$6.1M
Program in Molecular and Cellular BiosciencesT32GM071338 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MASLEN, CHERYL L · 2005 to 2020
$3.5M
NIDDK NIH HHS R01 DK057699NIGMS NIH HHS T32 GM071338
6 · The paper itself

Abstract

NMDA receptors (NMDARs) are Ca

Indexed as

Signal TransductionAdultAMP-Activated Protein KinasesAnimalsBiotinylationCalcium SignalingCell Line, TumorCell MembraneCells, CulturedHumansInsulinInsulin-Secreting CellsInsulin SecretionKATP ChannelsLeptinLigandsAMP-Activated Protein KinasesInsulinKATP ChannelsKCNB1 protein, humanKcnb1 protein, ratLeptinLigandsMembrane Transport ModulatorsReceptors, N-Methyl-D-AspartateShab Potassium ChannelsAMP-activated kinase (AMPK)calciumcalcium imagingelectrophysiologyglucoseglutamateion channel

Identifiers

PMID28768770
PMCPMC5602408
OpenAlexW2741748366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.