Evidence map›Paper›PMID 28768715›Full record

ArticleRNA (New York, N.Y.)2017

Architecture and dynamics of overlapped RNA regulatory networks.

Christopher P Lapointe, Melanie A Preston, Daniel Wilinski, Harriet A J Saunders, Zachary T Campbell, Marvin Wickens

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  8. Post-transcriptional control of fungal cell wall synthesis.Cell surface (Amsterdam, Netherlands) · 2022
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  16. Review
  17. Records of RNA locations in living yeast revealed through covalent marks.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christopher P LapointeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Melanie A PrestonDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Daniel WilinskiDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Harriet A J SaundersDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Zachary T CampbellDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Marvin WickensDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA wickens@biochem.wisc.edu.
University of Wisconsin–Madison · US

Funding

FUNCTION OF POLY(A) AND 3'UTRSR01GM050942 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI WICKENS, MARVIN P. · 1994 to 2020
$8.3M
NIGMS NIH HHS R01 GM050942
6 · The paper itself

Abstract

A single protein can bind and regulate many mRNAs. Multiple proteins with similar specificities often bind and control overlapping sets of mRNAs. Yet little is known about the architecture or dynamics of overlapped networks. We focused on three proteins with similar structures and related RNA-binding specificities-Puf3p, Puf4p, and Puf5p of

Indexed as

Gene Regulatory NetworksBinding SitesModels, MolecularNucleotidyltransferasesProtein BindingRNA-Binding ProteinsRNA, FungalRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsMPT5 protein, S cerevisiaeNucleotidyltransferasespoly U polymerasePUF3 protein, S cerevisiaePUF4 protein, S cerevisiaeRNA-Binding ProteinsRNA, FungalRNA, MessengerSaccharomyces cerevisiae Proteinsprotein–RNA interactionsprotein–RNA networksPUF proteinsRNA-binding proteinsRNA control

Identifiers

PMID28768715
PMCPMC5648032
OpenAlexW2949998542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.