Evidence map›Paper›PMID 28768685›Full record

ArticleThe Journal of cell biology2017

Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases.

Chris MacDonald, Robert C Piper

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. IST1 regulates select recycling pathways.Traffic (Copenhagen, Denmark) · 2024
    Article
  7. Article
  8. Discovery of a rapidly evolving yeast defense factor,Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. A second chance at yeast early endosomes.The Journal of cell biology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Frontiers in genetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chris MacDonaldDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA.ORCID 0000-0002-7450-600X
Robert C PiperDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA robert-piper@uiowa.edu.ORCID 0000-0001-9995-5699
University of Iowa · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Ubiquitin-Dependent Sorting in Endosomes and the TGNR01GM058202 · NIGMS · UNIVERSITY OF IOWA · PI PIPER, ROBERT C · 1998 to 2025
$8.9M
NIGMS NIH HHS R01 GM058202
6 · The paper itself

Abstract

Endocytosed cell surface membrane proteins rely on recycling pathways for their return to the plasma membrane. Although endosome-to-plasma membrane recycling is critical for many cellular processes, much of the required machinery is unknown. We discovered that yeast has a recycling route from endosomes to the cell surface that functions efficiently after inactivation of the

Indexed as

EndosomesMonomeric GTP-Binding ProteinsMultiprotein ComplexesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTOR Serine-Threonine KinasesAdaptor Proteins, Vesicular TransportGuanine Nucleotide Exchange FactorsMechanistic Target of Rapamycin Complex 1Adaptor Proteins, Vesicular TransportGtr1 protein, S cerevisiaeGTR2 protein, S cerevisiaeGuanine Nucleotide Exchange FactorsLTV1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 1Monomeric GTP-Binding ProteinsMultiprotein ComplexesSaccharomyces cerevisiae ProteinsSec7 guanine nucleotide exchange factorsTOR Serine-Threonine KinasesVAM6 protein, S cerevisiae

Identifiers

PMID28768685
PMCPMC5626546
OpenAlexW2741423701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.