Evidence map›Paper›PMID 28768167›Full record

ArticleCell metabolism2017

Burning Fat and Building Bone by FSH Blockade.

Carlos Henrique Sponton, Shingo Kajimura

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
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  9. Review
  10. Review
  11. Positive Effect of Gushukang on Type-H Vessel and Bone Formation.Frontiers in cell and developmental biology · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. FSH Beyond Fertility.Frontiers in endocrinology · 2019
    Review
  17. Modulation of Gonadotropins Activity by Antibodies.Frontiers in endocrinology · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Carlos Henrique SpontonDiabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA; Obesity and Comorbidities Research Center-OCRC, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
Shingo KajimuraDiabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA. Electronic address: skajimura@diabetes.ucsf.edu.
University of California, San Francisco · US

Funding

Molecular mechanisms of UCP1-independent pathways in metabolic healthR01DK097441 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Shingo Kajimura · 2012 to 2026
$5.9M
NIDDK NIH HHS R01 DK097441
6 · The paper itself

Abstract

The rise of follicle-stimulating hormone (FSH) is a hallmark of menopause associated with osteoporosis and visceral adiposity. In Nature, Zaidi and colleagues (Liu et al., 2017) report that blocking FSH action reduces body fat by promoting brown/beige fat thermogenesis, potentially providing a new intervention for the treatment of menopause-related metabolic diseases.

Indexed as

Follicle Stimulating HormoneThermogenesisAdipose TissueAdipose Tissue, BeigeBone and BonesFemaleHumansFollicle Stimulating Hormone

Identifiers

PMID28768167
PMCPMC9142816
OpenAlexW2739537376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.