Evidence map›Paper›PMID 28767770›Full record

SynthesisJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

Effects of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea: a systematic review and meta-analysis of six randomized controlled trials.

Qiang Lei, Yunhui Lv, Kai Li, Lei Ma, Guodong Du, Yan Xiang, Xuqing Li

Open access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  6. The treatment of mild OSA with CPAP or mandibular advancement device and the effect on blood pressure and endothelial function after one year of treatment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
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  11. Clinical Question: Can CPAP suppress cardiovascular events in resistant hypertension patients with obstructive sleep apnea?Hypertension research : official journal of the Japanese Society of Hypertension · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qiang Lei. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Yunhui Lv. Department of Respiratory Medicine, First People's Hospital of Yunnan Province, Kunming, China.
Kai Li. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Lei Ma. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Guodong Du. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Yan Xiang. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Xuqing Li. Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, China.
Kunming University of Science and Technology · CNFirst People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate systematically the effects of continuous positive airway pressure (CPAP) on blood pressure in patients with resistant hypertension and obstructive sleep apnea (OSA).

methodsThe Cochrane Library, PubMed, ScienceDirect, and the Web of Science were searched for studies investigating the effects of CPAP on blood pressure in patients with resistant hypertension and OSA. The selected studies underwent quality assessment and meta-analysis, as well as being tested for heterogeneity.

resultsSix randomized controlled trials were included in the meta-analysis. The pooled estimates of the changes in mean systolic blood pressure and mean diastolic blood pressure (as assessed by 24-h ambulatory blood pressure monitoring) were -5.40 mmHg (95% CI: -9.17 to -1.64; p = 0.001; I2 = 74%) and -3.86 mmHg (95% CI: -6.41 to -1.30; p = 0.00001; I2 = 79%), respectively.

conclusionsCPAP therapy can significantly reduce blood pressure in patients with resistant hypertension and OSA.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryContinuous Positive Airway PressureHumansHypertensionRandomized Controlled Trials as TopicSleep Apnea, Obstructive

Identifiers

PMID28767770
PMCPMC5790661
OpenAlexW2740077687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.