ArticlePloS one2017
Influence of exposure parameters and iterative reconstruction on automatic airway segmentation and analysis on MDCT-An ex vivo phantom study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Detection of Airway Remodeling in Asthma Using Bronchoscopic Optical Coherence Tomography.CHEST pulmonary · 2025Article
- GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography.Frontiers in medicine · 2023Article
- Feasibility of bronchial wall quantification in low- and ultralow-dose third-generation dual-source CT: An ex vivo lung study.Journal of applied clinical medical physics · 2020Article
- Influence of acquisition settings and radiation exposure on CT lung densitometry-An anthropomorphic ex vivo phantom study.PloS one · 2020Article
- Validation of the RayStation Monte Carlo dose calculation algorithm using a realistic lung phantom.Journal of applied clinical medical physics · 2019Article
- Influence of Inspiratory/Expiratory CT Registration on Quantitative Air Trapping.Academic radiology · 2019Article
- Reproducibility of an airway tapering measurement in computed tomography with application to bronchiectasis.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- Longitudinal airway remodeling in active and past smokers in a lung cancer screening population.European radiology · 2019Article
- Pulmonary quantitative CT imaging in focal and diffuse disease: current research and clinical applications.The British journal of radiology · 2018Review
- Standardized airway wall thickness Pi10 from routine CT scans of COPD patients as imaging biomarker for disease severity, lung function decline, and mortality.Therapeutic advances in respiratory diseaseArticle
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8 authors.
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Abstract
objectivesTo evaluate the influence of exposure parameters and raw-data-based iterative reconstruction (IR) on computer-aided segmentation and quantitative analysis of the tracheobronchial tree on multidetector computed tomography (MDCT). MATERIAL AND
methods10 porcine heart-lung-explants were mounted inside a dedicated chest phantom. MDCT was performed at 120kV and 80kV with 120, 60, 30 and 12 mAs each. All scans were reconstructed with filtered back projection (FBP) or IR, resulting in a total of 160 datasets. The maximum number of detected airway segments, most peripheral airway generation detected, generation-specific airway wall thickness (WT), total diameter (TD) and normalized wall thickness (pi10) were compared.
resultsThe number of detected airway segments decreased slightly with dose (324.8±118 at 120kV/120mAs vs. 288.9±130 at 80kV/30mAs with FBP, p<0.05) and was not changed by IR. The 20th generation was constantly detected as most peripheral. WT did not change significantly with exposure parameters and reconstruction algorithm across all generations: range 1st generation 2.4-2.7mm, 5th 1.0-1.1mm, and 10th 0.7mm with FBP; 1st 2.3-2.4mm, 5th 1.0-1.1mm, and 10th 0.7-0.8mm with IR. pi10 was not affected as well (range 0.32-0.34mm).
conclusionsExposure parameters and IR had no relevant influence on measured airway parameters even for WT <1mm. Thus, no systematic errors would be expected using automatic airway analysis with low-dose MDCT and IR.
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