Evidence map›Paper›PMID 28767514›Full record

ArticleEpidemiology (Cambridge, Mass.)2017

Interrelationships Between Walkability, Air Pollution, Greenness, and Body Mass Index.

Peter James, Marianthi-Anna Kioumourtzoglou, Jaime E Hart, Rachel F Banay, Itai Kloog, Francine Laden

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 4 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Association of Air Pollution With Adiposity Rates in Active Runners and Inactive People.American journal of human biology : the official journal of the Human Biology Council · 2025
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  18. Advancing Exposomic Research in Prenatal Respiratory Disease Programming.Immunology and allergy clinics of North America · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Peter JamesFrom the aDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; bDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA; cChanning Division of Network Medicine, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA; dDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY; and eThe Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Marianthi-Anna Kioumourtzoglou
Jaime E Hart
Rachel F Banay
Itai Kloog
Francine Laden
Harvard University · USBen-Gurion University of the Negev · ILColumbia University · US

Funding

Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI GIOVANNUCCI, EDWARD · 2000 to 2019
$77.8M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
CVD Epidemiology Training Program in Behavior, the Environment and Global HealthT32HL098048 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Goodarz Danaei, ERIC B RIMM · 2009 to 2026
$6.9M
DIET, PHYSICAL ACTIVITY, AND THE RELATIONSHIP BETWEEN AIR POLLUTION AND CVDR01ES017017 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI LADEN, FRANCINE · 2009 to 2012
$1.7M
High resolution measures of behavioral cancer risk factors from mobile technologyK99CA201542 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI JAMES, PETER · 2016 to 2016
$129k
NCI NIH HHS K99 CA201542NCI NIH HHS P01 CA087969NCI NIH HHS UM1 CA186107NHLBI NIH HHS T32 HL098048NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES017017NIEHS NIH HHS T32 ES007069
6 · The paper itself

Abstract

backgroundRecent studies have linked urban environmental factors and body mass index (BMI); however, such factors are often examined in isolation, ignoring correlations across exposures.

methodsUsing data on Nurses' Health Study participants living in the Northeastern United States in 2006, we estimated associations between neighborhood walkability (a composite of population density, street connectivity, and business access), greenness (from satellite imagery), and ambient air pollution (from satellite-based spatiotemporally resolved PM2.5 predictions and weighted monthly average concentrations of NO2 from up to five nearest monitors) and self-reported BMI using generalized additive models, allowing for deviations from linearity using penalized splines.

resultsAmong 23,435 women aged 60-87 years, we observed nonlinear associations between walkability and BMI and between PM2.5 and BMI in single-exposure models adjusted for age, race, and individual- and area-level socioeconomic status. When modeling all exposures simultaneously, only the association between walkability and BMI remained nonlinear and nonmonotonic. Increasing walkability was associated with increasing BMI at lower levels of walkability (walkability index <1.8), while increasing walkability was linked to lower BMI in areas of higher walkability (walkability index >1.8). A 10 percentile increase in walkability, right above 1.8 was associated with a 0.84% decrease in log BMI. The relationship between walkability and BMI existed only among younger participants (<71 years old).

conclusionsNeighborhood walkability was nonlinearly linked to lower BMI independent of air pollution and greenness. Our findings highlight the importance of accounting for nonlinear confounding by interrelated urban environmental factors when investigating associations between the environment and BMI.

Indexed as

PlantsWalkingAgedAged, 80 and overAir PollutionBody Mass IndexCohort StudiesFemaleHumansMiddle AgedNew EnglandNitrogen DioxideObesityParticulate MatterProspective StudiesResidence CharacteristicsNitrogen DioxideParticulate Matter

Identifiers

PMID28767514
PMCPMC5617802
OpenAlexW2742012416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.