ArticleGut microbes2018
Heritable components of the human fecal microbiome are associated with visceral fat.
Article in Gut microbes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed.
- Integrative evidence for causal links between gut microbiota and Schizophrenia: A Mendelian randomization and 16S rRNA study.Brain, behavior, & immunity - health · 2025Article
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- Scrutinizing microbiome determinism: why deterministic hypotheses about the microbiome are conceptually ungrounded.History and philosophy of the life sciences · 2024Article
- Advances in the mechanism of metformin with wide-ranging effects on regulation of the intestinal microbiota.Frontiers in microbiology · 2024Review
- Gut microbiome diversity, variability, and latent community types compared with shifts in body weight during the freshman year of college in dormitory-housed adolescents.Gut microbes · 2023Observational
- A Keystone Gut BacteriumFoods (Basel, Switzerland) · 2023Review
- The gut microbiome and regional fat distribution: Findings from the Baltimore Longitudinal Study of Aging.Obesity (Silver Spring, Md.) · 2023Article
- Combing fecal microbial community data to identify consistent obesity-specific microbial signatures and shared metabolic pathways.iScience · 2023Article
- Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota.Genetics, selection, evolution : GSE · 2022Article
- Article
- Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort.Nature genetics · 2022Article
- Exploring the role of gut microbiota in host feeding behavior among breeds in swine.BMC microbiology · 2022Article
- Dried chicory root improves bowel function, benefits intestinal microbial trophic chains and increases faecal and circulating short chain fatty acids in subjects at risk for type 2 diabetes.Gut microbiome (Cambridge, England) · 2022Article
- Gut microbiota: A new target for T2DM prevention and treatment.Frontiers in endocrinology · 2022Review
- Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.Frontiers in microbiology · 2022Article
- Study on the differences of gut microbiota composition between phlegm-dampness syndrome and qi-yin deficiency syndrome in patients with metabolic syndrome.Frontiers in endocrinology · 2022Article
- Host genetic control of gut microbiome composition.Mammalian genome : official journal of the International Mammalian Genome Society · 2021Review
- Effect of High-Fat Diet on the Intestinal Flora in Letrozole-Induced Polycystic Ovary Syndrome Rats.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Comparison Between the Gut Microbiota in Different Gastrointestinal Segments of Large-Tailed Han and Small-Tailed Han Sheep Breeds with High-Throughput Sequencing.Indian journal of microbiology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and its associated diseases are one of the major causes of death worldwide. The gut microbiota has been identified to have essential regulatory effects on human metabolism and obesity in particular. In a recent study we provided some insights into the link between the gut microbiota (GM) and adiposity, as well as host genetic modulation of these processes. Our results identify novel evidence of association between 6 adiposity phenotypes and faecal microbial operational taxonomic units (OTUs). Accumulation of visceral fat, a key risk factor for cardio-metabolic disease, has the strongest and most pervasive signature on the gut microbiota of the factors we examined. Furthermore, we observe that the adiposity-associated OTUs were classified as heritable and in some cases were also associated with host genetic variation at obesity-associated human candidate genes FHIT, TDRG1 and ELAVL4. This addendum confirms our previously published results in the TwinsUK cohort using a different approach to OTU clustering and multivariate analysis, and discusses further the importance of considering the GM as a complex ecosystem.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.