Evidence map›Paper›PMID 28767127›Full record

ArticleActa psychiatrica Scandinavica2017

Social functioning in patients with depressive and anxiety disorders.

I M J Saris, M Aghajani, S J A van der Werff, N J A van der Wee, B W J H Penninx

Abstract read
In one paragraph

Article in Acta psychiatrica Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Everyday Lives of Middle-Aged Persons with Multimorbidity: A Mixed Methods Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
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  10. Negative affect interacts with perceptual affective biases.Journal of psychopharmacology (Oxford, England) · 2026
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  12. Dopaminergic modulation of social reward anticipation in depression: neural effects of amisulpride versus placebo.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I M J SarisDepartment of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center and GGZ inGeest, Amsterdam, the Netherlands.ORCID 0000-0003-3970-5123
M AghajaniDepartment of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center and GGZ inGeest, Amsterdam, the Netherlands.
S J A van der WerffDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
N J A van der WeeDepartment of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.
B W J H PenninxDepartment of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center and GGZ inGeest, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdaptive social functioning is severely impeded in depressive and anxiety disorders, even after remission. However, a comprehensive overview is still lacking.

methodUsing data from the Netherlands Study of Depression and Anxiety (NESDA), behavioural (network size, social activities, social support) and affective (loneliness, affiliation, perceived social disability) indicators of social functioning were analyzed in patients with anxiety (N = 540), depressive (N = 393), comorbid anxiety and depressive disorders ('comorbid', N = 748), remitted participants (N = 621), and healthy control subjects (N = 650).

resultsAnalyses revealed an increasing trend of social dysfunction among patient groups, in patients with comorbid anxiety and depressive disorders, showing the most severe impairments, followed by depressed and anxious patients (P's < 0.001 for all social functioning indicators). Affective indicators showed the largest effect sizes (Cohen's d range from 0.13 to 1.76). We also found impairments in social functioning among remitted patients. Furthermore, perceived social disability among patients was predictive of still having a depressive and/or anxiety diagnosis 2 years later (P < 0.01).

conclusionsBehavioural but especially affective indicators of social functioning are impaired in patients with anxiety or depressive disorders and most in patients with comorbid disorders. After remission of affective psychopathology, residual impairments tend to remain, while social dysfunction in patients seems predictive of future psychopathology.

Indexed as

Social DesirabilitySocial SupportAdultAnxiety DisordersComorbidityCross-Sectional StudiesFemaleHumansLonelinessMajor Depressive DisorderMaleMiddle AgedNetherlandsSocial Participationanxietydepressionsocial functioning

Identifiers

PMID28767127
PMCPMC5601295

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.