Evidence map›Paper›PMID 28766938›Full record

ArticleInorganic chemistry2017

Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK.

Andrea J North, John A Karas, Michelle T Ma, Philip J Blower, Uwe Ackermann, Jonathan M White, Paul S Donnelly

Abstract read
In one paragraph

Article in Inorganic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Rhenium-186-labeledRSC advances · 2026
    Article
  2. Review
  3. Article
  4. Synthesis and Preclinical Evaluation of Three NovelMolecules (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Rhenium and technetium complexes of thioamide derivatives of pyridylhydrazine that bind to amyloid-β plaques.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea J NorthThe School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , 3010, Victorria, Australia.
John A KarasThe School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , 3010, Victorria, Australia.
Michelle T MaDivision of Imaging Sciences and Biomedical Engineering, King's College London , Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, U.K.ORCID http://orcid.org/0000-0002-3349-7346
Philip J BlowerDivision of Imaging Sciences and Biomedical Engineering, King's College London , Fourth Floor Lambeth Wing, St Thomas' Hospital, London SE1 7EH, U.K.
Uwe AckermannDepartment of Molecular Imaging and Therapy, Department of Medicine, University of Melbourne , Austin Health, Studley Road, Heidelberg, Victoria 3010, Australia.
Jonathan M WhiteThe School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , 3010, Victorria, Australia.ORCID http://orcid.org/0000-0002-0707-6257
Paul S DonnellyThe School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , 3010, Victorria, Australia.ORCID http://orcid.org/0000-0001-5373-0080

Funding

Cancer Research UK 16463Wellcome Trust
6 · The paper itself

Abstract

This research aimed to develop new tumor targeted theranostic agents taking advantage of the similarities in coordination chemistry between technetium and rhenium. A γ-emitting radioactive isotope of technetium is commonly used in diagnostic imaging, and there are two β

Indexed as

Coordination ComplexesDrug StabilityHydrazinesLigandsPeptides, CyclicPyridinesRheniumSemicarbazonesTheranostic NanomedicineThioamidesCoordination Complexescyclic (arginyl-glycyl-aspartyl-phenylalanyl-lysyl)HydrazinesLigandsoctreotate, Tyr(3)-Peptides, CyclicPyridinesRheniumSemicarbazonesThioamides

Identifiers

PMID28766938
PMCPMC5569669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.