Evidence map›Paper›PMID 28766918›Full record

ReviewPhotodermatology, photoimmunology & photomedicine2018

The skin microbiome and immune system: Potential target for chemoprevention?

Mohammad Asif Sherwani, Saba Tufail, Anum Fatima Muzaffar, Nabiha Yusuf

Open access · bronzeAbstract readReview
In one paragraph

Review in Photodermatology, photoimmunology & photomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Mud therapy and skin microbiome: a review.International journal of biometeorology · 2018
    Pooled it
  3. Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Review
  4. Importance of human microbiome: an update.Frontiers in microbiomes · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Field cancerization in dermatology.Revista da Associacao Medica Brasileira (1992) · 2024
    Article
  10. Review
  11. Microbial Diversity of the Chinese Tiger Frog (Animals : an open access journal from MDPI · 2022
    Article
  12. Article
  13. The Human Microbiota and Skin Cancer.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. [The skin microbiome-useful for diagnosis and therapy?]Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mohammad Asif SherwaniDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Saba TufailDepartment of Biochemistry, Faculty of Medicine, Aligarh Muslim University, Aligarh, India.
Anum Fatima MuzaffarDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Nabiha YusufDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID http://orcid.org/0000-0001-5730-0037
University of Alabama at Birmingham · USAligarh Muslim University · IN

Funding

Mechanisms elicited by type I interferons in cutaneous photocarcinogenesisR01AR071157 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YUSUF, NABIHA · 2016 to 2020
$1.8M
NIAMS NIH HHS R01 AR071157
6 · The paper itself

Abstract

There has been increasing interest in understanding the role of the human microbiome in skin diseases. Microbiome studies are being utilized in skin cancer research in numerous ways. Commensal bacteria are being studied as a potential tool to judge the biggest environmental risk of skin cancer, ultraviolet (UV) radiation. Owing to the recognized link of skin microbes in the process of inflammation, there have been theories linking commensal bacteria to skin cancer. Viral metagenomics has also provided insight into virus linked forms of skin cancers. Speculations can be drawn for skin microbiome that in a manner similar to gut microbiome, they can be involved in chemoprevention of skin cancer. Nonetheless, there are definitely huge gaps in our knowledge of the relationship of microbiome and skin cancers, especially in relation to chemoprevention. The utilization of microbiome in skin cancer research seems to be a promising field and may help yield novel skin cancer prevention and treatment options. This review focuses on recent utilization of the microbiome in skin cancer research, and it explores the potential of utilizing the microbiome in prevention, earlier diagnosis, and treatment of skin cancers.

Indexed as

MicrobiotaAnimalsGastrointestinal MicrobiomeHumansPrebioticsProbioticsSkinSkin NeoplasmsUltraviolet RaysVirus DiseasesVitamin DPrebioticsVitamin Dchemopreventionimmune systemskin microbiome

Identifiers

PMID28766918
PMCPMC7289174
OpenAlexW2740079045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.