ArticleBirth defects research2017
Population-based case-control study of the association between weather-related extreme heat events and neural tube defects.
Article in Birth defects research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Pooled it
- A systematic review and meta-analysis on heat thresholds for maternal health and birth outcomes.Nature communications · 2026Pooled it
- Thermal indices for assessing the impact of outdoor thermal environments on human health: a systematic review of epidemiological studies.International journal of biometeorology · 2025Pooled it
- Prenatal ambient temperature and risk for schizophrenia.Schizophrenia research · 2022Pooled it
- Impacts of High Environmental Temperatures on Congenital Anomalies: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Heat spells and birth and peripartum pregnancy complications in Germany: a scoping review.Archives of gynecology and obstetrics · 2026Article
- Climate Change and Reproductive Health.Endocrine reviews · 2025Review
- Associations between exposure to extreme ambient heat and neural tube defects in Georgia, USA: A population-based case-control study.Environmental research · 2024Article
- Extreme Heat and Pregnancy Outcomes: A Scoping Review of the Epidemiological Evidence.International journal of environmental research and public health · 2022Article
- Assessing the effects of disasters and their aftermath on pregnancy and infant outcomes: A conceptual model.International journal of disaster risk reduction : IJDRR · 2021Article
- A population-based case-control study of the association between weather-related extreme heat events and low birthweight.Journal of developmental origins of health and disease · 2021Article
- Independent and Combined Effects of Heatwaves andEnvironmental health perspectives · 2020Article
- Associations between fine particulate matter, extreme heat events, and congenital heart defects.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Maternal ambient heat exposure during early pregnancy in summer and spring and congenital heart defects - A large US population-based, case-control study.Environment international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundElevated body core temperature has been shown to have teratogenic effects in animal studies. Our study evaluated the association between weather-related extreme heat events (EHEs) in the summer season and neural tube defects (NTDs), and further investigated whether pregnant women with a high pregestational body mass index (BMI) have a greater risk of having a child with NTDs associated with exposure to EHE than women with a normal BMI.
methodsWe conducted a population-based case-control study among mothers of infants with NTDs and mothers of infants without major birth defects, who participated in the National Birth Defects Prevention Study and had at least 1 day of the third or fourth week postconception during summer months. EHEs were defined using the 95
resultsOverall, we did not observe a significant association between EHEs and NTDs. At the climate region level, consistently elevated but not statistically significant estimates were observed for at least 2 consecutive days with daily universal apparent maximum temperature above the 95
conclusionEHEs occurring during the relevant developmental window of embryogenesis do not appear to appreciably affect the risk of NTDs. Future studies should refine exposure assessment, and more completely account for maternal activities that may modify the effects of weather exposure. Birth Defects Research 109:1482-1493, 2017.© 2017 Wiley Periodicals, Inc.
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