Evidence map›Paper›PMID 28766563›Full record

ArticleThe American journal of gastroenterology2017

Editorial: The Effect of Bias on Estimation of Improved Survival After Diagnosis of Barrett's Esophagus.

Liam Zakko, Kavel Visrodia, Kenneth K Wang, Prasad G Iyer

Open access · greenAbstract readComment
In one paragraph

Article in The American journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Liam ZakkoDepartment of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Kavel VisrodiaDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Kenneth K WangDepartment of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Prasad G IyerDepartment of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · US

Funding

Weight loss-induced Microbiome and Adipokine Changes in Barrett's EsophagusU54CA163004 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABRAMS, JULIAN, RUSTGI, ANIL K · 2011 to 2022
$12.5M
Esophageal Cancer from Cells to Population: A Multiscale ApproachU01CA182940 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HUR, CHIN, INADOMI, JOHN MATTHEW · 2013 to 2017
$3.3M
NCI NIH HHS U01 CA182940NCI NIH HHS U54 CA163004
6 · The paper itself

Abstract

Adjustments for lead and length time bias has been used when examining apparent survival advantages from screening procedures. However, these estimates depend on several assumptions and are modeled from malignancies that are fairly common and large cohorts are available. In smaller retrospective cohorts, adjustments themselves may be based on estimates that may not be biological nor statistically accurate, which can lead to divergent results as has been found in several recent studies of screening in Barrett's esophagus. Only a prospective randomized controlled trial can really determine the benefit though this may not feasible.

Indexed as

Barrett EsophagusBiasEsophageal NeoplasmsEsophagusHumansProspective StudiesRetrospective Studies

Identifiers

PMID28766563
PMCPMC5574169
OpenAlexW2741681878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.