Evidence map›Paper›PMID 28766243›Full record

Observational studyDigestive diseases and sciences2017

Cost of Illness in Inflammatory Bowel Disease.

Nagesh Kamat, C Ganesh Pai, M Surulivel Rajan, Asha Kamath

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Confronting the hidden cost of diagnostic delay in diagnosis and treatment initiation: Inflammatory bowel disease as model to understand chronic diseases.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  4. Economic burden borne by patients due to diagnostic delays in inflammatory bowel disease: Insights from a survey of newly diagnosed patients.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Observational
  5. Review
  6. Observational
  7. Inflammatory bowel disease in south Asia: a scoping review.The lancet. Gastroenterology & hepatology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nagesh KamatDepartment of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, 576104, India.
C Ganesh PaiDepartment of Gastroenterology and Hepatology, Kasturba Medical College, Manipal University, Manipal, Karnataka, 576104, India. cg.pai@manipal.edu.
M Surulivel RajanDepartment of Pharmacotherapy, UNTS College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, 76107, USA.
Asha KamathDepartment of Community Medicine, Kasturba Medical College, Manipal University, Manipal, 576104, India.
Kasturba Medical College, Manipal · INManipal Academy of Higher Education · INUniversity of North Texas Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrequent relapses sometimes necessitating hospitalization and the absence of pharmacological cure contribute to substantial healthcare costs in inflammatory bowel diseases (IBDs). The costs of health care in Indian patients with IBD are unknown.

aimTo evaluate the annual costs for treating Crohn's disease and ulcerative colitis.

methodsA prevalence-based, micro-costing method was used to assess the components of annual costs in a prospective, observational study conducted in a tertiary healthcare center enrolled over a 24-month period beginning of July 2014.

resultsAt enrollment, 43/59 (72.88%) patients with UC and 18/25 (72%) with CD were in remission. The annual median (IQR) cost per UC and CD patient in remission was INR 43,140 (34,357-51,031) [USD $707 (563-836)] and INR 43,763.5 (32,202-57,372) [USD $717 (527-940)], respectively, and in active disease was INR 52,436.5 (49,229-67,567.75) [$859 (807-1107)] and INR 72,145 (49,447-92,212) [USD $1182 (811-1512)], respectively. Compared with remission, active disease had a 1.4-fold higher cost for CD as compared to UC. In both groups, the greatest component of direct costs was drugs. Thirteen (22%) and 7 (28%) patients with UC and CD needed hospitalization accounting for 23.1 and 20.4% of the total costs, respectively. At one year, direct costs surmounted indirect costs in UC and CD (p < 0.001). Productivity losses contributed to 18.5 and 16% of the overall costs for UC and CD, respectively.

conclusionThis first, panoptic, health economic study for IBD from India shows that the costs are driven by medication, productivity losses, and not merely hospitalization alone.

Indexed as

Cost of IllnessAdolescentAdultAgedFemaleFollow-Up StudiesHumansIndiaInflammatory Bowel DiseasesMaleMiddle AgedProspective StudiesYoung AdultCost of illnessGastroenterologyInflammatory bowel diseasePharmacoeconomics

Identifiers

PMID28766243
OpenAlexW2741656354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.