ArticleJournal of anesthesia2017
Acute kidney injury after pediatric liver transplantation: incidence, risk factors, and association with outcome.
Article in Journal of anesthesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.Paediatric anaesthesia · 2026Pooled it
- Risk factors for acute kidney injury after pediatric liver transplantation: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- The use of urinary biomarkers to predict acute kidney injury in children after liver transplant.Pediatric transplantation · 2020Trial
- Associations of Intraoperative Hypotension and Vasopressor Administration With Postoperative Acute Kidney Injury in Children Undergoing Liver Transplantation: A Retrospective Cohort Study.Paediatric anaesthesia · 2026Article
- Outcomes of Acute Kidney Injury After Pediatric Liver Transplantation: A 1-Year Follow-Up.Clinical transplantation · 2024Article
- Postoperative hypoalbuminemia and outcomes of pediatric liver transplantation.BMC pediatrics · 2024Article
- Acute kidney injury after living-related liver transplantation in infants with biliary atresia: A retrospective study.Pediatric discovery · 2024Article
- Incidence and Risk Factors of Acute Kidney Injury in Pediatric Liver Transplant Patients: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Transplanting the Liver for a New Life: Can the Kidney Throw in a Spanner?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Epidemiology data on the cost and outcomes associated with pediatric acute kidney injury.Pediatric research · 2023Article
- Kidney disease in children with heart or liver transplant.Pediatric nephrology (Berlin, Germany) · 2021Review
- Acute Kidney Injury and Renal Regional Oxygen Saturation During Pediatric Liver Transplantation.Annals of transplantation · 2020Article
- Effect of sevoflurane and propofol on acute kidney injury in pediatric living donor liver transplantation.Annals of translational medicine · 2019Article
- Incidence and Impact of Acute Kidney Injury after Liver Transplantation: A Meta-Analysis.Journal of clinical medicine · 2019Article
- Acute kidney injury after pediatric liver transplantation.Journal of anesthesia · 2017Article
- Patient blood management in India - Review of current practices and feasibility of applying appropriate standard of care guidelines. A position paper by an interdisciplinary expert group.Journal of anaesthesiology, clinical pharmacologyReview
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeData on the incidence of, risk factors for, and association with outcomes of acute kidney injury (AKI) after pediatric liver transplantation are scarce. We conducted a retrospective cohort study to determine the incidence of AKI after pediatric liver transplantation. In addition, we examined risk factors for AKI and association of AKI with outcomes.
methodsThis study included 156 children aged between 3 months and 18 years undergoing liver transplantation at Kyoto University Hospital. AKI was defined according to the Kidney Disease: Improving Global Outcomes guidelines based on serum creatinine and urine output. We used multivariable logistic regression with stepwise variable selection to identify independent risk factors for AKI.
resultsAKI occurred in 72 patients (46.2%); 34 (21.8%) had stage 1, 32 (20.5%) had stage 2, and 6 (3.8%) had stage 3 AKI. Factors independently associated with the development of AKI were increased preoperative total bilirubin level (adjusted odds ratio, 1.04 per 1 mg/dl; 95% confidence interval, 1.01-1.09; P = 0.026) and increased intraoperative blood loss (adjusted odds ratio, 1.03 per 10 ml/kg; 95% confidence interval, 1.00-1.06; P = 0.022). AKI was significantly associated with prolonged hospitalization (median, 61 vs. 46 days; P = 0.028). In-hospital mortality rate was 4.2% in patients with AKI and 3.6% in those without AKI (P = 1.000).
conclusionThe incidence of AKI after pediatric liver transplantation was 46.2%. Increased preoperative total bilirubin level and increased intraoperative blood loss were independently associated with the development of AKI. AKI was associated with prolonged hospitalization.
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