Evidence map›Paper›PMID 28765780›Full record

ArticleNutrition research and practice2017

Associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length in Korean adults.

Hyewon Wang, Hyungjo Kim, Inkyung Baik

Open access · hybridAbstract read
In one paragraph

Article in Nutrition research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hyewon WangDepartment of Foods and Nutrition, College of Science and Technology, Kookmin University, 77, Jeongnung-ro, Seongbuk-gu, Seoul 02707, Korea.
Hyungjo KimDepartment of Foods and Nutrition, College of Science and Technology, Kookmin University, 77, Jeongnung-ro, Seongbuk-gu, Seoul 02707, Korea.
Inkyung BaikDepartment of Foods and Nutrition, College of Science and Technology, Kookmin University, 77, Jeongnung-ro, Seongbuk-gu, Seoul 02707, Korea.
Kookmin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTelomere length is a useful biomarker for determining general aging status. Some studies have reported an association between alcohol consumption and telomere length in a general population; however, it is unclear whether the alcohol flush reaction, which is an alcohol-related trait predominantly due to acetaldehyde dehydrogenase deficiency, is associated with telomere length. This cross-sectional study aimed to evaluate the associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length (LTL). SUBJECTS/

methodsThe study included 1,803 Korean adults. Participants provided blood specimens for LTL measurement assay and reported their alcohol drinking status and the presence of an alcohol flush reaction via a questionnaire-based interview. Relative LTL was determined by using a quantitative polymerase chain reaction. Statistical analysis used multiple linear regression models stratified by sex and age groups, and potential confounding factors were considered.

resultsAge-specific analyses showed that heavy alcohol consumption (> 30 g/day) was strongly associated with a reduced LTL in participants aged ≥ 65 years (

conclusionsThe results suggest that older alcohol drinkers, particularly those with the alcohol flush reaction, may have an accelerated aging process.

Indexed as

agingAlcoholaldehyde dehydrogenasetelomere

Identifiers

PMID28765780
PMCPMC5537543
OpenAlexW2726202109

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.