Evidence map›Paper›PMID 28765756›Full record

ArticleJournal of arrhythmia2017

Wavefront direction and cycle length affect left atrial electrogram amplitude.

Kazuki Iso, Ichiro Watanabe, Rikitake Kogawa, Yasuo Okumura, Koichi Nagashima, Keiko Takahashi, Ryuta Watanabe, Masaru Arai, Kimie Ohkubo, Toshiko Nakai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Initial experience of the High-Density Grid catheter in patients undergoing catheter ablation for atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Article
  3. Article
  4. Review
  5. Left atrial voltage mapping: defining and targeting the atrial fibrillation substrate.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kazuki IsoDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Ichiro WatanabeDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Rikitake KogawaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Yasuo OkumuraDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Koichi NagashimaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Keiko TakahashiDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Ryuta WatanabeDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Masaru AraiDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Kimie OhkuboDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Toshiko NakaiDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Atsushi HirayamaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Oyaguchi-kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Mizuki NikaidoNihon Kohden Corporation, Tokyo, Japan.
Nihon University · JPNihon Kohden (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between atrial electrogram (EGM) characteristics in atrial fibrillation (AF) and those in sinus rhythm (SR) are generally unknown. The activation rate and direction may affect EGM characteristics. We examined characteristics of left atrial (LA) EGMs obtained during pacing from different sites.

methodsThe study included 10 patients undergoing pulmonary vein isolation for AF. Atrial EGMs were recorded from a 64-pole basket catheter placed in the LA, and bipolar EGM amplitudes from the distal electrode pair (1-2) and proximal electrode pair (6-7) from 8 splines were averaged. The high right atrium (HRA), proximal coronary sinus (CSp), and distal coronary sinus (CSd) were paced at 600 ms and 300 ms.

resultsWhen the LA voltage at SR was ≥1.5 mV, bipolar voltages of the HRA were greater than those of the CSp, which were greater than those of the CSd, regardless of the pacing cycle length. The shorter pacing cycle length resulted in a reduction of the LA EGM voltage at sites of SR voltage ≥1.5 mV, but no significant difference was seen at sites where the SR EGM amplitude was between >0.5 and <1.5 mV. No significant differences were seen in intra-basket conduction times between pacing cycle lengths of 600 ms and 300 ms at any pacing site.

conclusionThe rate and direction-dependent reduction of the amplitude of atrial EGMs may explain, in part, the voltage discordance during SR and AF.

Indexed as

Atrial fibrillationAtrial pacingLeft atrial voltagePacing rate

Identifiers

PMID28765756
PMCPMC5529329
OpenAlexW2588353094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.