Evidence map›Paper›PMID 28765690›Full record

ReviewWorld journal of gastroenterology2017

Diarrhea after bariatric procedures: Diagnosis and therapy.

Yves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  13. Intestinal secretory mechanisms and diarrhea.American journal of physiology. Gastrointestinal and liver physiology · 2022
    Review
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yves M BorbélyYves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.
Alice OsterwalderYves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.
Dino KröllYves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.
Philipp C NettYves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.
Roman A InglinYves M Borbély, Alice Osterwalder, Dino Kröll, Philipp C Nett, Roman A Inglin, Clinic for Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, 3004 Bern, Switzerland.
University Hospital of Bern · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diarrhea after bariatric procedures, mainly those with malabsorptive elements including Roux-Y Gastric Bypass and Biliopancreatic Diversion, is common and an essential determinant of quality of life and micro- and macronutrient deficiencies. Bariatric surgery is the only sustainably successful method to address morbid obesity and its comorbidities, particularly gaining more and more importance in the specific treatment of diabetic patients. Approximately half a million procedures are annually performed around the world, with numbers expected to rise drastically in the near future. A multitude of factors exert their influence on bowel habits; preoperative comorbidities and procedure-related aspects are intertwined with postoperative nutritional habits. Diagnosis may be challenging owing to the characteristics of post-bariatric surgery anatomy with hindered accessibility of excluded segments of the small bowel and restriction at the gastric level. Conventional testing measures, if available, generally yield low accuracy and are usually not validated in this specific population. Limited trials of empiric treatment are a practical alternative and oftentimes an indispensable part of the diagnostic process. This review provides an overview of causes for chronic post-bariatric surgery diarrhea and details the particularities of its diagnosis and treatment in this specific patient population. Topics of current interest such as the impact of gut microbiota and the influence of bile acids on morbid obesity and especially their role in diarrhea are highlighted in order to provide a better understanding of the specific problems and chances of future treatment in post-bariatric surgery patients.

Indexed as

DiarrheaGastric BypassHumansIntestinal DiseasesPostoperative ComplicationsBariatric surgeryBile acids and saltsBlind loop syndromeDiarrheaDumping syndromeGut microbiotaMalabsorptionMalnutritionSteatorrhea

Identifiers

PMID28765690
PMCPMC5514634
OpenAlexW2735743318

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.