Evidence map›Paper›PMID 28765612›Full record

ArticleScientific reports2017

Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover's Distance.

Yongxin Chen, Filemon Dela Cruz, Romeil Sandhu, Andrew L Kung, Prabhjot Mundi, Joseph O Deasy, Allen Tannenbaum

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Matricial Wasserstein-1 Distance.IEEE control systems letters · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongxin ChenMemorial Sloan Kettering Cancer Center, Department of Medical Physics, New York, 10064, USA.ORCID 0000-0002-1459-6365
Filemon Dela CruzMemorial Sloan Kettering Cancer Center, Department of Pediatrics, New York, 10064, USA.
Romeil SandhuStony Brook University, Department of Biomedical Informatics, Stony Brook, 11794, USA.
Andrew L KungMemorial Sloan Kettering Cancer Center, Department of Pediatrics, New York, 10064, USA.
Prabhjot MundiColumbia University, Department of Medical Oncology, New York, 10032, USA.
Joseph O DeasyMemorial Sloan Kettering Cancer Center, Department of Medical Physics, New York, 10064, USA.
Allen TannenbaumStony Brook University, Departments of Computer Science and Applied Mathematics & Statistics, Stony Brook, 11794, USA. allen.tannenbaum@stonybrook.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
WHITE MATTER ARCHITECTURE FROM DT-MRIP41RR013218 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON · 1998 to 2011
$30.6M
Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
NCI NIH HHS P30 CA008748NCRR NIH HHS P41 RR013218NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

In this note, we combined pediatric sarcoma data from Columbia University with adult sarcoma data collected from TCGA, in order to see if one can automatically discern a unique pediatric cluster in the combined data set. Using a novel clustering pipeline based on optimal transport theory, this turned out to be the case. The overall methodology may find uses for the classification of data from other biological networking problems.

Indexed as

Cluster AnalysisGene Expression ProfilingAge FactorsBiostatisticsColombiaHumansPattern Recognition, AutomatedSarcoma

Identifiers

PMID28765612
PMCPMC5539155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.