Evidence map›Paper›PMID 28765503›Full record

ArticleThe oncologist2017

Advance Directives, Hospitalization, and Survival Among Advanced Cancer Patients with Delirium Presenting to the Emergency Department: A Prospective Study.

Ahmed F Elsayem, Eduardo Bruera, Alan Valentine, Carla L Warneke, Geri L Wood, Sai-Ching J Yeung, Valda D Page, Julio Silvestre, Patricia A Brock, Knox H Todd

Open access · bronzeAbstract read
In one paragraph

Article in The oncologist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Advance directives in the emergency department.Journal of the American College of Emergency Physicians open · 2020
    Article
  10. Patient Perspectives on Advance Care Planning via a Patient Portal.The American journal of hospice & palliative care · 2019
    Article
  11. Association of emergency department admission and early inpatient palliative care consultation with hospital mortality in a comprehensive cancer center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Article
  12. Observational
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ahmed F ElsayemDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA aelsayem@mdanderson.org.
Eduardo BrueraDepartments of Palliative, Rehabilitation, and Integrative Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Alan ValentineDepartment of Psychiatry, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Carla L WarnekeDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Geri L WoodThe University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Sai-Ching J YeungDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Valda D PageDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Julio SilvestreDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Patricia A BrockDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
Knox H ToddDepartment of Emergency Medicine, The University of Texas Health Science Center at Houston School of Nursing, Houston, Texas, USA.
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

backgroundTo improve the management of advanced cancer patients with delirium in an emergency department (ED) setting, we compared outcomes between patients with delirium positively diagnosed by both the Confusion Assessment Method (CAM) and Memorial Delirium Assessment Scale (MDAS), or group A ( MATERIALS AND

methodsIn an oncologic ED, we assessed 243 randomly selected advanced cancer patients for delirium using the CAM and the MDAS and for presence of advance directives. Outcomes extracted from patients' medical records included hospital and intensive care unit admission rate and overall survival (OS).

resultsHospitalization rates were 82%, 77%, and 49% for groups A, B, and C, respectively (

conclusionDelirium assessed by either CAM or MDAS was associated with worse survival and more hospitalization in patients with advanced cancer in an oncologic ED. Many advanced cancer patients with delirium in ED lack advance directives. Delirium should be assessed regularly and should trigger discussion of goals of care and advance directives. IMPLICATIONS FOR PRACTICE: Delirium is a devastating condition among advanced cancer patients. Early diagnosis in the emergency department (ED) should improve management of this life-threatening condition. However, delirium is frequently missed by ED clinicians, and the outcome of patients with delirium is unknown. This study finds that delirium assessed by the Confusion Assessment Method or the Memorial Delirium Assessment Scale is associated with poor survival and more hospitalization among advanced cancer patients visiting the ED of a major cancer center, many of whom lack advance directives. Therefore, delirium in ED patients with cancer should trigger discussion about advance directives.

Indexed as

Advance DirectivesDeliriumEmergency Service, HospitalNeoplasmsAgedChinaFemaleHospitalizationHumansLength of StayMaleMedical OncologyMiddle AgedProspective StudiesAdvance directivesCancerDeliriumEmergencySurvival

Identifiers

PMID28765503
PMCPMC5679826
OpenAlexW2741231809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.