Evidence map›Paper›PMID 28765367›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map.

Kyle P Eagen, Erez Lieberman Aiden, Roger D Kornberg

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 193 citations in OpenAlex.

  1. Article
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  8. Polycomb-mediated 3D chromatin interactions in gene regulation.Current opinion in genetics & development · 2026
    Review
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  10. Review
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  12. Review
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  20. Review

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kyle P EagenDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; kornberg@stanford.edu eagen@northwestern.edu.
Erez Lieberman AidenThe Center for Genome Architecture, Baylor College of Medicine, Houston, TX 77030.
Roger D KornbergDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; kornberg@stanford.edu eagen@northwestern.edu.
Stanford University · USBaylor College of Medicine · US

Funding

Structure of the Eukaryote Transcription ApparatusR01AI021144 · NIAID · STANFORD UNIVERSITY · PI KORNBERG, ROGER D · 1985 to 2018
$10.3M
Molecular Biophysics Training Program at StanfordT32GM008294 · NIGMS · STANFORD UNIVERSITY · PI HUANG, KERWYN C. · 1989 to 2019
$7.4M
RNA POLYMERASE II TRANSCRIPTION SYSTEM FROM YEASTR01GM036659 · NIGMS · STANFORD UNIVERSITY · PI KORNBERG, ROGER D · 1986 to 2016
$4.7M
RNA POLYMERASE II TRANSCRIPTION SYSTEM FROM YEASTR37GM036659 · NIGMS · STANFORD UNIVERSITY · PI KORNBERG, ROGER D · 1998 to 2008
$4.6M
Exploring how the genome folds through proximity ligation and sequencingDP2OD008540 · OD · BROAD INSTITUTE, INC. · PI LIEBERMAN-AIDEN, EREZ · 2011 to 2016
$3.0M
Supplement - Beyond pairwise DNA contacts: exploring higher-order genome structure using proximity ligationU01HL130010 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LIEBERMAN-AIDEN, EREZ · 2015 to 2019
$2.3M
NHLBI NIH HHS U01 HL130010NIAID NIH HHS R01 AI021144NIGMS NIH HHS R01 GM036659NIGMS NIH HHS R37 GM036659NIGMS NIH HHS T32 GM008294NIH HHS DP2 OD008540
6 · The paper itself

Abstract

The locations of chromatin loops in

Indexed as

AnimalsChromatinDNA-Binding ProteinsDrosophilaDrosophila ProteinsHigh-Throughput Nucleotide SequencingPolycomb Repressive Complex 1Promoter Regions, GeneticRepressor ProteinsChromatinDNA-Binding ProteinsDrosophila ProteinsPolycomb Repressive Complex 1Repressor Proteinschromosome structureDNA loopsgene repressionnuclear architecturePolycomb

Identifiers

PMID28765367
PMCPMC5565414
OpenAlexW2951956418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.