Evidence map›Paper›PMID 28765325›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Diverse

Britta Weigelt, Iñaki Comino-Méndez, Ino de Bruijn, Lei Tian, Jane L Meisel, Isaac García-Murillas, Charlotte Fribbens, Ros Cutts, Luciano G Martelotto, Charlotte K Y Ng and 14 more

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 1 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 1 synthesis or guideline pooled it, 251 citations in OpenAlex.

  1. Pooled it
  2. Multicenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Trial
  3. Mechanisms and disease relevance of DNA break repair pathway choice.Nature reviews. Molecular cell biology · 2026
    Review
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 3 countries.

Britta WeigeltDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. weigeltb@mskcc.org nicholas.turner@icr.ac.uk.
Iñaki Comino-MéndezBreast Cancer Now Research Centre, Institute of Cancer Research, London, United Kingdom.
Ino de BruijnDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Lei TianDepartment of Cancer Biology, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jane L MeiselDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Isaac García-MurillasBreast Cancer Now Research Centre, Institute of Cancer Research, London, United Kingdom.
Charlotte FribbensBreast Cancer Now Research Centre, Institute of Cancer Research, London, United Kingdom.
Ros CuttsBreast Cancer Now Research Centre, Institute of Cancer Research, London, United Kingdom.
Luciano G MartelottoDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Charlotte K Y NgDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Raymond S LimDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Pier SelenicaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Salvatore PiscuoglioDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Carol AghajanianDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Larry NortonDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Rajmohan MuraliDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
David M HymanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Laetitia BorsuDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Maria E ArcilaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Jason KonnerDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Jorge S Reis-FilhoDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
Roger A GreenbergDepartment of Cancer Biology, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Mark E RobsonDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Nicholas C TurnerBreast Cancer Now Research Centre, Institute of Cancer Research, London, United Kingdom. weigeltb@mskcc.org nicholas.turner@icr.ac.uk.
Memorial Sloan Kettering Cancer Center · USBreast Cancer Now · GBRoyal Marsden NHS Foundation Trust · GBUniversity of Pennsylvania · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The Role of Focal Oncogene Amplifications in Lung CancerP01CA129243 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Piro Lito · 2007 to 2026
$31.2M
NCI NIH HHS P01 CA129243NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsCell-Free Nucleic AcidsDrug Resistance, NeoplasmFemaleGerm-Line MutationHumansMiddle AgedMutationOvarian NeoplasmsPlatinumPoly(ADP-ribose) Polymerase InhibitorsBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanCell-Free Nucleic AcidsPlatinumPoly(ADP-ribose) Polymerase Inhibitors

Identifiers

PMID28765325
PMCPMC5728372
OpenAlexW2741214285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.