Evidence map›Paper›PMID 28765217›Full record

ArticlemBio2017

RIP-Seq Suggests Translational Regulation by L7Ae in

Michael Daume, Michael Uhl, Rolf Backofen, Lennart Randau

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Auto-regulatory feedback by RNA-binding proteins.Journal of molecular cell biology · 2019
    Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael DaumeMax-Planck-Institute for Terrestrial Microbiology, Marburg, Germany.
Michael UhlBioinformatics Group, Albert Ludwig University Freiburg, Freiburg, Germany.
Rolf BackofenBioinformatics Group, Albert Ludwig University Freiburg, Freiburg, Germany.
Lennart RandauMax-Planck-Institute for Terrestrial Microbiology, Marburg, Germany lennart.randau@mpi-marburg.mpg.de.
Max Planck Institute for Terrestrial Microbiology · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L7Ae is a universal archaeal protein that recognizes and stabilizes kink-turn (k-turn) motifs in RNA substrates. These structural motifs are widespread in nature and are found in many functional RNA species, including ribosomal RNAs. Synthetic biology approaches utilize L7Ae/k-turn interactions to control gene expression in eukaryotes. Here, we present results of comprehensive RNA immunoprecipitation sequencing (RIP-Seq) analysis of genomically tagged L7Ae from the hyperthermophilic archaeon

Indexed as

Gene Expression Regulation, ArchaealProtein BiosynthesisSequence Analysis, RNAArchaeal ProteinsEscherichia coliImmunoprecipitationProtein BindingRibosomal ProteinsRNA, ArchaealRNA-Binding ProteinsRNA, UntranslatedSulfolobus acidocaldariusArchaeal ProteinsRibosomal ProteinsRNA, ArchaealRNA-Binding ProteinsRNA, UntranslatedArchaeagene regulationRNA binding proteinsRNA structure

Identifiers

PMID28765217
PMCPMC5539422
OpenAlexW2740655334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.