Evidence map›Paper›PMID 28765080›Full record

ArticleHormones and behavior2017

Activation of extrasynaptic δ-GABA

Laverne C Melón, Zachary T Nolan, Delphine Colar, Eileen M Moore, Stephen L Boehm

Open access · greenAbstract read
In one paragraph

Article in Hormones and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Gene Deficiency of δ Subunit-Containing GABANeurochemical research · 2025
    Article
  4. GABAergic compounds for the treatment of alcohol use disorder.International review of neurobiology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. An Emerging Circuit Pharmacology of GABATrends in pharmacological sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Laverne C MelónAddiction Neuroscience, Department of Psychology, Indiana University/Purdue University-Indianapolis, Indianapolis, IN 46202, USA; Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA.
Zachary T NolanPenn State College of Medicine, Hershey, PA 17033, USA.
Delphine ColarAddiction Neuroscience, Department of Psychology, Indiana University/Purdue University-Indianapolis, Indianapolis, IN 46202, USA.
Eileen M MooreCenter for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, CA 92120, USA.
Stephen L BoehmAddiction Neuroscience, Department of Psychology, Indiana University/Purdue University-Indianapolis, Indianapolis, IN 46202, USA. Electronic address: slboehm@iupui.edu.
Indiana University – Purdue University Indianapolis · USPenn State Milton S. Hershey Medical Center · USSan Diego State University · USTufts University · USUniversity of Indianapolis · US

Funding

TRAINING GRANT ON GENETICS ASPECTS OF ALCOHOLISMT32AA007462 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CRISTINE L CZACHOWSKI · 1985 to 2026
$10.7M
Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
GABAergic Mechanisms in the Modulation of Binge-Like Ethanol Intake in MiceR01AA016789 · NIAAA · STATE UNIVERSITY OF NY,BINGHAMTON · PI BOEHM, STEPHEN LEE · 2009 to 2013
$1.8M
Alcohol intake and aversion during adolescence in 8 inbred mouse strainsF31AA018910 · NIAAA · STATE UNIVERSITY OF NY,BINGHAMTON · PI MOORE, EILEEN MARIE · 2009 to 2011
$76k
NIAAA NIH HHS F31 AA018910NIAAA NIH HHS R01 AA016789NIAAA NIH HHS T32 AA007462NIGMS NIH HHS K12 GM074869
6 · The paper itself

Abstract

Recent reports support higher than expected rates of binge alcohol consumption among women and girls. Unfortunately, few studies have assessed the mechanisms underlying this pattern of intake in females. Studies in males suggest that alcohol concentrations relevant to the beginning stages of binge intoxication may selectively target tonic GABAergic inhibition mediated by GABA

Indexed as

Alcohol DrinkingAnimalsBinge DrinkingEstrous CycleEthanolFemaleGABA-A Receptor AgonistsHippocampusIsoxazolesLocomotionMaleMiceMice, Inbred C57BLPeriaqueductal GrayReceptors, GABA-ASynapsesEthanolGABA-A Receptor AgonistsgaboxadolIsoxazolesReceptors, GABA-AAlcoholBinge drinkingDeltaExtrasynapticFemalesGABA(A)MouseTHIPTonic inhibition

Identifiers

PMID28765080
PMCPMC5623082
OpenAlexW2756440222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.