Evidence map›Paper›PMID 28764691›Full record

Trial reportBMC musculoskeletal disorders2017

Kneeling and standing up from a chair as performance-based tests to evaluate knee function in the high-flexion range: a randomized controlled trial comparing a conventional and a high-flexion TKA design.

Paul J P van der Ven, Sebastiaan van de Groes, Jorrit Zelle, Sander Koëter, Gerjon Hannink, Nico Verdonschot

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00899041 (In-vivo Study Investigating the Difference in Functional Outcome Between Two Types of Knee Prostheses), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00899041 nacompletednot on this map

In-vivo Study Investigating the Difference in Functional Outcome Between Two Types of Knee Prostheses: the Sigma FB (Depuy, J&J, UK; Standard Implant) and the Sigma RP-F (Depuy, J&J, UK; High-flexion Implant)

TypeinterventionalSponsorRadboud University Medical CenterRan2008 to 2013Enrolled67ConditionsArthroplasty, Replacement, KneeArmsTotal Knee Arthroplasty (TKA)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul J P van der Ven611 Orthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, PO Box 9101, 6500HB, Nijmegen, The Netherlands.
Sebastiaan van de Groes611 Orthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, PO Box 9101, 6500HB, Nijmegen, The Netherlands.
Jorrit Zelle611 Orthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, PO Box 9101, 6500HB, Nijmegen, The Netherlands.
Sander KoëterDepartment of Orthopaedics, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Gerjon Hannink611 Orthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, PO Box 9101, 6500HB, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-9526-3775
Nico Verdonschot611 Orthopaedic Research Laboratory, Department of Orthopaedics, Radboud University Medical Center, PO Box 9101, 6500HB, Nijmegen, The Netherlands. nico.verdonschot@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe compared the functional outcome between conventional and high-flexion total knee arthroplasty (TKA) using kneeling and sit-to-stand tests at 1 year post-operative. In addition, the patient's daily functioning, pain and satisfaction were quantified using questionnaires.

methodsWe randomly assigned 56 patients to receive either a conventional or a high-flexion TKA. Primary outcomes were maximum flexion angle and maximum thigh-calf contact measured during kneeling at 1 year post operatively. Secondary outcomes were the angular knee velocity and ground reaction force ratio measured during sit-to-stand performance tests, and questionnaires.

resultsAt one year post-operative, maximum knee flexion during kneeling was higher for the high-flexion TKA group (median 128.02° (range 108-146)) compared to the conventional TKA group (119.13° (range 72-135)) (p = 0.03). Maximum thigh-calf contact force was higher for the high flexion TKA group (median 17.82 N (range 2.98-114.64)) compared to the conventional TKA group (median 9.37 N (range 0.33-46.58))(p = 0.04). The sit-to-stand tests showed a significantly higher angular knee velocity in the conventional TKA group (12.12 rad/s (95%CI 0.34-23.91); p = 0.04). There were no significant differences between groups in ground reaction force ratios and patient-reported outcome scores.

conclusionAlthough no differences were found in patient-reported outcome scores, differences in performance-based tests were clearly apparent. Standing up from a chair at 90° of knee flexion appeared to be easier for the conventional group. The kneeling test revealed significantly higher weight-bearing knee flexion for the high-flex group. Hence, if kneeling is an important activity for a patient a high-flex design may be recommendable.

trial registrationThe study was retrospectively registered in ClinicalTrials.gov under identifier NCT00899041 (date of registration: May 11, 2009).

Indexed as

AgedArthroplasty, Replacement, KneeDouble-Blind MethodFemaleHumansKnee JointKnee ProsthesisMaleMiddle AgedOutcome Assessment, Health CarePostureProspective StudiesFunctional outcomeHigh-flexionKneelingPerformance-based testsSit-to-standTotal knee arthroplasty

Identifiers

PMID28764691
PMCPMC5540509

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.