Evidence map›Paper›PMID 28764192›Full record

ArticleJournal of clinical and diagnostic research : JCDR2017

Evaluation of Antiulcer Activity of Peltophorum Pterocarpum.

Bhupalam Pradeepkumar, C P Bhavyamadhuri, Y Padmanabhareddy, K V Veerabhadrappa, Gorantla Narayana, C Haranath, K Somasekharreddy, Akkiraju Sudheer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bhupalam PradeepkumarAssociate Professor and Head, Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
C P BhavyamadhuriPharmacy Student, Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
Y PadmanabhareddyPrincipal, Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
K V VeerabhadrappaAssociate Professor, Department of Pharmacognasy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
Gorantla NarayanaAssociate Professor, Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
C HaranathAssociate Professor, Department of Pharmaceutics, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
K SomasekharreddyAssociate Professor, Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
Akkiraju SudheerAssociate Professor, Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh, India.
Jawaharlal Nehru Technological University Anantapur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

aimTo evaluate the antiulcer activity of methanolic extract of the leaves of MATERIALS AND

methodsThe rats were divided into four groups as control, standard, test 1 (extract: 100 mg/kg) and test 2 (extract: 200 mg/kg) with six rats in each group. Gastric lesions were induced by oral administration of indomethacin (20 mg/kg) followed by pylorus ligation. Standard group of animals were treated with misoprostol and test group of animals were treated with MEPP at doses of 100 and 200 mg/kg. To determine the antiulcer activity of extract, mean ulcer index, free acidity and total acidity were evaluated.

resultsUlcer index was significantly decreased at p<0.01 in MEPP treated groups as compared to control group. Total and free acidity was significantly decreased at p<0.01 in MEPP treated groups as compared to control group. Histological analysis also supported the gastro protective effect of MEPP treated groups when compared with control groups.

conclusionThe study revealed that MEPP exhibited potential antiulcer activity and showed dose dependent antiulcer effect.

Indexed as

IndomethacinMisoprostolPylorus ligationUlcer index

Identifiers

PMID28764192
PMCPMC5535385
OpenAlexW2729889304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.