Evidence map›Paper›PMID 28763638›Full record

SynthesisJournal of affective disorders2017

A systematic review of growth curve mixture modelling literature investigating trajectories of perinatal depressive symptoms and associated risk factors.

Emily Baron, Judith Bass, Sarah M Murray, Marguerite Schneider, Crick Lund

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of affective disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.

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  18. Trajectories of antenatal depression and adverse pregnancy outcomes: A prospective cohort study.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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  20. Adolescents' internalizing and externalizing symptom trajectories in relation to early-life parental depressive symptoms.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Emily BaronAlan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa. Electronic address: emily.baron@uct.ac.za.
Judith BassDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.
Sarah M MurrayDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States.
Marguerite SchneiderAlan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.
Crick LundAlan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa; Center for Global Mental Health, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Johns Hopkins University · USUniversity of Cape Town · ZAKing's College London · GB

Funding

Global Mental Health Training ProgramT32MH103210 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Judith Karen Bass, Sarah Sutherlin-McIvor Murray · 2015 to 2026
$4.0M
Shared Research Project ComponentU19MH095699 · NIMH · UNIVERSITY OF CAPE TOWN · PI ALEM, ATALAY, LUND, CRICK · 2011 to 2015
$2.6M
NIMH NIH HHS T32 MH103210NIMH NIH HHS U19 MH095699
6 · The paper itself

Abstract

backgroundThe aim of this study was to review the growth curve mixture modelling (GCMM) literature investigating trajectories of perinatal maternal depressive symptoms and associated risk factors.

methodsA systematic search of peer-reviewed articles published until November 2015 was conducted in seven databases. Articles using GCMM to identify trajectories of perinatal depressive symptoms were considered. Symptoms had to be assessed at least three times, anytime from pregnancy to two years postpartum (PROSPERO; 2016:CRD42016032600).

resultsEleven studies met inclusion criteria. All reported a low risk trajectory, characterised by stable low depressive symptoms throughout the perinatal period. A stable moderate-high or high symptom trajectory was reported in eight of 11 studies, suggesting a high-risk group with persistent depressive symptoms. Six studies also reported transient trajectories, with either increasing, decreasing or episodic depressive symptoms. None of the demographic, personality or clinical characteristics investigated systematically differentiated groups of women with different symptom trajectories, within or across studies. Thus, it is difficult to differentiate women at high or low risk of specific perinatal depression trajectories. LIMITATIONS: A meta-analysis was not possible. The studies' settings and inclusion criteria limit the generalisability of the findings to low-risk, middle- to high-income women.

conclusionsRelatively similar trajectories of perinatal depressive symptoms were identified across studies. Evidence on factors differentiating women assigned to different trajectories was inconsistent. Research with larger samples and in more diverse settings is needed to inform services and policies on how and when to effectively identify subgroups of women at high risk of perinatal depression.

Indexed as

Depression, PostpartumFemaleHumansMaternal HealthMothersPregnancyRisk FactorsSocial AdjustmentYoung AdultDepressive symptomsGrowth mixture modellingPostpartumPregnancyRisk factorsTrajectory

Identifiers

PMID28763638
PMCPMC5592733
OpenAlexW2736865397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.